Journal of Organic Chemistry 2006-03-17

Mild organocatalytic alpha-methylenation of aldehydes.

Anniina Erkkilä, Petri M Pihko

Index: J. Org. Chem. 71 , 2538, (2006)

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Abstract

A rapid and extremely convenient method for alpha-methylenation of aldehydes with aqueous formaldehyde is described. Two optimal catalytic systems are presented that allow short reaction times and afford the functionalized products in good to excellent yields (up to 99%) and chemoselectivity.

Structure	Name/CAS No.	Molecular Formula	Articles
	2-Methyl-2-propanyl (2-oxoethyl)carbamate CAS:89711-08-0	C₇H₁₃NO₃

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Mild organocatalytic alpha-methylenation of aldehydes.

Abstract

Related Compounds