Tetrahedron

Simple and practical halogenation of arenes, alkenes and alkynes with hydrohalic acid/H 2 O 2 (or TBHP)

NB Barhate, AS Gajare, RD Wakharkar, AV Bedekar

Index: Barhate, Nivrutti B.; Gajare, Anil S.; Wakharkar, Radhika D.; Bedekar, Ashutosh V. Tetrahedron, 1999 , vol. 55, # 36 p. 11127 - 11142

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Citation Number: 115

Abstract

A simple protocol for the halogenation of arenes utilizing a combination of aqueous hydrogen peroxide (34%) or tert-butylhydroperoxide (70%) and hydrohalic acid is presented. A similar procedure of oxyhalogenation involving the in situ generation of positive halogen reagents is applied for the preparation of vicinal trans-dibromoalkanes and dichloroalkanes from alkenes. The reaction of alkenes with a combination of hydrochloric ...