Chemical Communications

Metal-free aerobic oxidative coupling of amines to imines

L Liu, S Zhang, X Fu, CH Yan

Index: Liu, Lianghui; Zhang, Siyu; Fu, Xuefeng; Yan, Chun-Hua Chemical Communications, 2011 , vol. 47, # 36 p. 10148 - 10150

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Citation Number: 53

Abstract

Oxidative coupling of primary amines to imines is achieved with high to moderate yields by refluxing suspensions of amines and water under one atmosphere dioxygen without any additives. Tandem acid-free aza Diels–Alder reactions for synthesis of N-alkyl-4-pyridones are also accomplished.