Helvetica Chimica Acta

A Different Role of Meldrum's Acid in the Biginelli Reaction

J Svĕtlík, L Veizerová

Index: Svetlik, Jan; Veizerova, Lucia Helvetica Chimica Acta, 2011 , vol. 94, # 2 p. 199 - 205

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Citation Number: 14

Abstract

Abstract A Biginelli-type condensation using Meldrum's acid has been accomplished in refluxing AcOH to give 6-substituted dihydropyrimidine-2, 4-(1H, 3H)-diones. In contrast to other aldehydes, the three-component reaction with salicylaldehyde led to an oxygen-