PF-06835919
Published date: 2020-04-10 15:43:47
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Name | Ketohexokinase inhibitor 1 | CAS# | 2102501-84-6 |
|---|---|---|---|---|
| Price | $450.0/10mg | Purity | 98.0% | |
| Stocking Period |
1 Day | Stock | 3 | |
| Product Webpage: | http://www.dcchemicals.com/product_show-PF-06835919.html | |||
| Detail
Product Information
PF-06835919, also known as MDK1846, is a potent ketohexokinase (KHK) inhibitor. PF-06835919 is reported in patent US 20170183328 A1, example 4. Increased fructose consumption and its subsequent metabolism have been implicated in hepatic steatosis, dyslipidemia, obesity, and insulin resistance in humans. Since ketohexokinase (KHK) is the principal enzyme responsible for fructose metabolism, identification of a selective KHK inhibitor may help to further elucidate the effect of KHK inhibition on these metabolic disorders. |
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