Salmon Calcitonin Acetate
Modify Date: 2026-07-01 18:06:58
Salmon Calcitonin Acetate structure
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Common Name | Salmon Calcitonin Acetate | ||
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| CAS Number | 47931-85-1 | Molecular Weight | 3431.853 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C145H240N44O48S2 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
Use of Salmon Calcitonin AcetateCalcitonin salmon, a calcium regulating hormone, is a dual-action amylin and calcitonin receptor agonist, could stimulate bone formation and inhibit bone resorption. Sequence: Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2(Disulfide bridge: Cys1-Cys7). |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | calcitonin |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Calcitonin salmon, a calcium regulating hormone, is a dual-action amylin and calcitonin receptor agonist, could stimulate bone formation and inhibit bone resorption. Sequence: Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2(Disulfide bridge: Cys1-Cys7). |
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| Related Catalog | |
| Target |
Amylin, Calcitonin receptor[1]. |
| In Vivo | Oral Calcitonin salmon treatment dose-dependently attenuates fasting and non-fasted hyperglycaemia during the intervention period. At the end of the study period, oral Calcitonin salmon treatment by dose decreases diabetic hyperglycaemia by ~9 mM and reduces HbA1c levels by 1.7%. Furthermore, a pronounced reduction in glucose excursions is dose-dependently observed for oral Calcitonin salmon treatment during oral glucose tolerance test. In addition, oral Calcitonin salmon treatment sustains hyperinsulinaemia and attenuates hyperglucagonaemia and hypersecretion of total glucagon-like peptide-1 predominantly in the basal state. Lastly, oral Calcitonin salmon treatment dose-dependently improves pancreatic beta-cell function and beta-cell area at study end[1]. |
| Animal Admin | Rats[1] Male ZDF rats are treated with oral Calcitonin salmon (sCT: 0.5, 1.0 or 2 mg/kg) or oral vehicle twice daily from age 8 to 18 weeks. Zucker lean rats serve as control group. Fasting and non-fasted blood glucose, glycosylated haemoglobin (HbA1c) and levels of pancreas and incretin hormones are determined. Oral glucose tolerance test and i.p. glucose tolerance test were compared, and beta-cell area and function were evaluated[1]. |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Molecular Formula | C145H240N44O48S2 |
| Molecular Weight | 3431.853 |
| Exact Mass | 3429.713379 |
| PSA | 1558.81000 |
| LogP | -12.48 |
| Index of Refraction | 1.677 |
| Storage condition | −20°C |
| Water Solubility | 0.05 M acetic acid: 1 mg/mL, clear, colorless |
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Personal Protective Equipment | Eyeshields;Faceshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Hazard Codes | Xi |
| Safety Phrases | 22-24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | EV8000000 |
This table lists relevant public references with title, journal and publication metadata for this compound.
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The use of polyion complex micelles to enhance the oral delivery of salmon calcitonin and transport mechanism across the intestinal epithelial barrier.
Biomaterials 33(34) , 8881-92, (2012) The objective of the present study was to demonstrate the effect of polyanionic copolymer mPEG-grafted-alginic acid (mPEG-g-AA)-based polyion complex (PIC) micelles on enhancing the oral absorption of... |
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[Osteoporotic fractures: not only in females].
Rev. Med. Suisse 10(424) , 767-8, (2014)
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Decline in calcitonin receptor expression in osteocytes with age.
J. Endocrinol. 221(2) , 181-91, (2014) We have previously shown that co-administration of the transient osteoclast inhibitor, salmon calcitonin (sCT), blunts the anabolic effect of parathyroid hormone (PTH) in young rats and increases oste... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: qHTS for Inhibitors of Polymerase Kappa
Source: NCGC
Target: DNA polymerase kappa [Homo sapiens]
External Id: PolK100
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Name: qHTS for Inhibitors of binding or entry into cells for Marburg Virus
Source: NCGC
Target: gene 4 small orf - Marburg virus
External Id: VSVM-OFFLINE
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Name: qHTS for Inhibitors of binding or entry into cells for Lassa Virus
Source: NCGC
Target: N/A
External Id: VSVL-OFFLINE
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| MFCD00133859 |
| tz-ct |
| Calcitoran |
| Calcitoninsalmon |
| Thyrocalcitonin |
| calcimar |
| Calcitonin salmon |
| Calcitonin |
| SALMON |
| Salmon Calcium |
| Salmon Calcitonin Acetate |
| EINECS 256-342-8 |
| Salmotonin |
| Salcitonin |
| Salcatonin |
| cibacalcin |
| Salmon Calcitonin |
| Calcitonin (salmon) |
| CYS-SER-ASN-LEU-SER-THR-CYS-VAL-LEU-GLY-LYS-LEU-SER-GLN-GLU-LEU-HIS-LYS-LEU-GLN-THR-TYR-PRO-ARG-THR-ASN-THR-GLY-SER-GLY-THR-PRO-NH2(DISULFIDE BRIDGE CYS1-CYS7) |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: How is the water solubility of calcitonin? |
| A: Water solubility of calcitonin: 0.05 M acetic acid: 1 mg/mL, clear, colorless. |
| Q: What is the molecular formula of calcitonin? |
| A: Molecular formula of calcitonin is C145H240N44O48S2. |
| Q: What is the molecular weight of calcitonin? |
| A: Molecular weight of calcitonin is 3431.853. |
| Q: What English synonyms does calcitonin have? |
| A: English synonyms of calcitonin: MFCD00133859, tz-ct, Calcitoran, Calcitoninsalmon, Thyrocalcitonin, calcimar, Calcitonin salmon, Calcitonin, SALMON, Salmon Calcium, Salmon Calcitonin Acetate, EINECS 256-342-8, Salmotonin, Salcitonin, Salcatonin, cibacalcin, Salmon Calcitonin, Calcitonin (salmon), CYS-SER-ASN-LEU-SER-THR-CYS-VAL-LEU-GLY-LYS-LEU-SER-GLN-GLU-LEU-HIS-LYS-LEU-GLN-THR-TYR-PRO-ARG-THR-ASN-THR-GLY-SER-GLY-THR-PRO-NH2(DISULFIDE BRIDGE CYS1-CYS7). |
| Q: What is the safety information for calcitonin? |
| A: Safety information for calcitonin: 22-24/25. |
| Q: What is the polar surface area (PSA) of calcitonin? |
| A: Polar surface area (PSA) of calcitonin is 1558.81000. |
| Q: What is the English name of calcitonin? |
| A: The English name of calcitonin is calcitonin. |
| Q: What are the storage conditions for calcitonin? |
| A: Storage conditions for calcitonin: −20°C. |
| Q: What are the uses of calcitonin? |
| A: Main uses of calcitonin: Calcitonin salmon, a calcium regulating hormone, is a dual-action amylin and calcitonin receptor agonist, could stimulate bone formation and inhibit bone resorption. Sequence: Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2(Disulfide bridge: Cys1-Cys7). |
| Q: What is the CAS number of calcitonin? |
| A: CAS number of calcitonin is 47931-85-1. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Henan Tianfu Chemical Co., Ltd. |