| Name | Aslan003 | CAS# | 1035688-66-4 | |
|---|---|---|---|---|
| Price | $600.0/100mg $950.0/250mg $1900.0/1g | Purity | 98.0% | |
| Stocking Period |
1 Day | Stock | 3 | |
| Product Webpage: | https://www.dcchemicals.com/product_show-Aslan003.html | |||
| Detail
Product Information
ASLAN003 is an orally active and potent Dihydroorotate Dehydrogenase (DHODH) inhibitor with an IC50 of 35 nM for human DHODH enzyme. ASLAN003 inhibits protein synthesis via activation of AP-1 transcription factors. ASLAN003 induces apoptosis and substantially prolongs survival in acute myeloid leukemia (AML) xenograft mice. |