Name | (-)-Terreic acid | CAS# | 121-40-4 | |
---|---|---|---|---|
Price | $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg | Purity | 98.0% | |
Stocking Period |
3 Day | Stock | 3 | |
Product Webpage: | https://www.dcchemicals.com/product_show-Terreic_Acid.html |
Detail
Product Information
Terreic Acid is a cell-permeable quinone epoxide that selectively inhibits Bruton’s tyrosine kinase (BTK) catalytic activity (IC50s = 10 and 3 μM for basal and activation levels, respectively). Terreic Acid recapitulated the phenotypic defects of btk mutant mast cells in high-affinity IgE receptor-stimulated wild-type mast cells without affecting the enzymatic activities and expressions of many other signaling molecules, including those of protein kinase C. Terreic acid is a covalent inhibitor of the bacterial cell wall biosynthetic enzyme UDP-N-acetylglucosamine 1-carboxyvinyltransferase (MurA) . |