Pexidartinib hydrochloride (PLX-3397)
Published date: 2020-12-18 22:54:27
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Name | Pexidartinib hydrochloride (PLX-3397) | CAS# | 2040295-03-0 |
|---|---|---|---|---|
| Price | $200.0/100mg $400.0/250mg $800.0/1g | Purity | 98.0% | |
| Stocking Period |
3 Day | Stock | 3 | |
| Product Webpage: | https://www.dcchemicals.com/product_show-PLX3397_hydrochloride.html | |||
| Detail
Product Information
Pexidartinib hydrochloride (PLX-3397 hydrochloride) is a potent, orally active, selective, and ATP-competitive colony stimulating factor 1 receptor (CSF1R or M-CSFR) and c-Kit inhibitor, with IC50s of 20 and 10 nM, respectively. Pexidartinib hydrochloride exhibits 10- to 100-fold selectivity for c-Kit and CSF1R over other related kinases. Pexidartinib hydrochloride induces cell apoptosis and has anti-cancer activity. |
DC Chemicals Limited
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