Rineterkib(ERK-IN-1;compound B)
Published date: 2021-12-17 15:49:26
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Name | Rineterkib | CAS# | 1715025-32-3 |
|---|---|---|---|---|
| Price | ￥850.0/25mg | Purity | 98.0% | |
| Stocking Period |
1 Day | Stock | 3 | |
| Product Webpage: | https://www.dcchemicals.com/product_show-Rineterkib.html | |||
| Detail
Product Information
Rineterkib, also known as LTT-462 or ERK-IN-1, is a RAF and ERK1/2 inhibitor which has demonstrated preclinical activity in multiple MAPK activated cancer cells and xenograft models. LTT462 binds to and inhibits ERK, thereby preventing the activation of ERK-mediated signal transduction pathways. This results in the inhibition of ERK-dependent tumor cell proliferation and survival. The mitogen-activated protein kinase (MAPK)/ERK pathway is upregulated in numerous tumor cell types and plays a key role in tumor cell proliferation, differentiation and survival. |
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