| Name | HPK1-IN-7 | CAS# | 2320462-65-3 | |
|---|---|---|---|---|
| Price | ¥850.0/100mg ¥1700.0/250mg ¥3600.0/1g | Purity | 98.0% | |
| Stocking Period |
1 Day | Stock | 3 | |
| Product Webpage: | https://www.dcchemicals.com/product_show-hpk1-in-7.html | |||
| Detail
Product Information
HPK1-IN-7 is a potent, orally active HPK1 (hematopoietic progenitor kinase 1, MAP4K1) inhibitor (IC50=2.6 nM) with excellent family and kinome selectivity. HPK1-IN-7 shows selectivity against IRAK4 (59 nM) and GLK (140 nM). HPK1-IN-7 shows robust efficacy against MC38 syngeneic tumor model in combination with anti-PD1. |