FD223
Published date: 2021-12-17 15:49:26
|
Name | FD223 | CAS# | 2050524-24-6 |
|---|---|---|---|---|
| Price | ￥Inquiry/1g | Purity | 98.9% | |
| Stocking Period |
1 Day | Stock | In Stock | |
| Product Webpage: | https://www.dcchemicals.com/product_show-fd223.html | |||
| Detail
Product Information
FD223 is a potent and selective phosphoinositide 3-kinase delta (PI3Kδ) inhibitor. FD223 displays high potency (IC50=1 nM) and good selectivity over other isoforms (IC50s of 51 nM, 29 nM and 37 nM, respectively for α, β and γ). FD223 exhibits efficient inhibition of the proliferation of acute myeloid leukemia (AML) cell lines by suppressing p-AKT Ser473 thus causing G1 phase arrest during the cell cycle. FD223 has potential for the research of leukemia such as AML. |
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