IMS2186

Published date: 2022-11-29 15:44:27

IMS2186 Structure
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Name IMS2186 CAS# 1031206-36-6
Price ¥Inquiry/1g Purity 98.9%
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 Detail Product Information
IMS2186 is an anti-proliferative and anti-angiogenic agent. IMS2186 blocks the cell cycle at G2 and inhibits the production of PGE2/TNF-α. IMS2186 inhibits cell growth in vitro in tumor cells, non-transformed fibroblasts, and retinal pigment epithelial cells. IMS2186 inhibits angiogenesis (IC50 = 0.1 μM) and cell migration. Intraocular injection of IMS2186 could be a long-lasting effective treatment for CNV (choroidal neovascularization) in AMD (age-related macular degeneration) with a reduction in scarring and related visual loss.

Supplier/Manufacture

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