FLLL32

Modify Date: 2025-08-25 20:15:20

FLLL32 structure	Common Name	FLLL32
	CAS Number	1226895-15-3	Molecular Weight	464.55
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₈H₃₂O₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of FLLL32

FLLL32 is a STAT3 inhibitor derived from the natural product curcumin. FLLL32 retains the cellular response to cytokines with anti-tumor activity[1].

Name	flll32
Synonym	More Synonyms

Description	FLLL32 is a STAT3 inhibitor derived from the natural product curcumin. FLLL32 retains the cellular response to cytokines with anti-tumor activity[1].
Related Catalog	Signaling Pathways >> Stem Cell/Wnt >> STAT Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> STAT
Target	STAT3[1]
In Vitro	FLLL32 specifically reduces STAT3 phosphorylation at Tyr705 (pSTAT3) and induces apoptosis at micromolar amounts in human melanoma cell lines and primary melanoma cultures[1].
References	[1]. Bill MA, et al. The small molecule curcumin analog FLLL32 induces apoptosis in melanoma cells via STAT3inhibition and retains the cellular response to cytokines with anti-tumor activity. Mol Cancer. 2010 Jun 25;9:165.

Molecular Formula	C₂₈H₃₂O₆
Molecular Weight	464.55
Exact Mass	464.22000
PSA	71.06000
LogP	5.53630
InChIKey	NQDROBVIYYEMDQ-WFYKWJGLSA-N
SMILES	COc1ccc(C=CC(=O)C2(C(=O)C=Cc3ccc(OC)c(OC)c3)CCCCC2)cc1OC
Storage condition	-20℃

Name: Viability qHTS for spleen associated tyrosine kinase inhibitor (SYKi) naive MV4-11 ce...
Source: NCGC
External Id: s-sky_synergy-MV-411_N-CTG72-MIPE_NPC_NPACT_Kinase-p1

Name: Primary qHTS for inhibitors of NSP2Pro chikungunya virus (CHIKV)
Source: NCGC
External Id: APP-Toga-CHIKV-nsp2-p

Name: Primary qHTS for Inhibitors of N-terminal methyltransferase 1 (NTMT1): MTaseGlo Assay
Source: NCGC
External Id: NTMT1-p-MTaseGlo

Name: Primary Screen for Target Class Profiling of Small Molecule Inhibitors of Methyltrans...
Source: NCGC
External Id: MTASE-p

Name: Primary qHTS Assay for Inhibitors of Recombinant Selenoprotein Glutathione Peroxidase...
Source: NCGC
External Id: GPx1-biochemical-p4-p7

Name: Identification of activators of human fumarate hydratase by quantitative high-through...
Source: NCGC
Target: FH fumarate hydratase [Homo sapiens (human)]
External Id: FUM001

Name: Inhibition of JAK2 at 5 uM by high throughput assay
Source: ChEMBL
Target: Tyrosine-protein kinase JAK2
External Id: CHEMBL2175197

Name: Primary qHTS for inhibitors of nuclear receptor binding SET domain protein 2 (NSD2) i...
Source: NCGC
External Id: NSD2-synergy-p-2C

Name: Primary qHTS for inhibitors of nuclear receptor binding SET domain protein 2 (NSD2) i...
Source: NCGC
External Id: NSD2-synergy-p-9B

Name: Viability qHTS for spleen associated tyrosine kinase inhibitor (SYKi) drug resistant ...
Source: NCGC
External Id: s-sky_synergy-MV-411_DR-CTG72-MIPE_NPC_NPACT_Kinase-p1

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MFCD22200575

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: FLLL32
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Purity: 98.0%
Delivery: 10 Day
Contact: Yang
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Price: ￥1001/10 mM * 1 mL in DMSO

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FLLL32

Use of FLLL32

Names

FLLL32 Biological Activity

Chemical & Physical Properties

FLLL32Bioassay

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.