SKLB1002

Modify Date: 2025-08-27 16:53:56

SKLB1002 structure	Common Name	SKLB1002
	CAS Number	1225451-84-2	Molecular Weight	320.390
	Density	1.5±0.1 g/cm3	Boiling Point	522.4±60.0 °C at 760 mmHg
	Molecular Formula	C₁₃H₁₂N₄O₂S₂	Melting Point	193 °C
	MSDS	Chinese USA	Flash Point	269.7±32.9 °C
	Symbol	GHS06	Signal Word	Danger

Use of SKLB1002

SKLB1002 is a novel and potent VEGFR-2 inhibitor with an IC50 value of 32 nM.

Name	2-(6,7-dimethoxyquinazolin-4-yl)sulfanyl-5-methyl-1,3,4-thiadiazole
Synonym	More Synonyms

Density	1.5±0.1 g/cm3
Boiling Point	522.4±60.0 °C at 760 mmHg
Melting Point	193 °C
Molecular Formula	C₁₃H₁₂N₄O₂S₂
Molecular Weight	320.390
Flash Point	269.7±32.9 °C
Exact Mass	320.040161
PSA	123.56000
LogP	2.40
Vapour Pressure	0.0±1.3 mmHg at 25°C
Index of Refraction	1.687
InChIKey	RQVGFDBMONQTBC-UHFFFAOYSA-N
SMILES	COc1cc2ncnc(Sc3nnc(C)s3)c2cc1OC
Storage condition	<0°C

Symbol	GHS06
Signal Word	Danger
Hazard Statements	H301
Precautionary Statements	P301 + P310 + P330
Hazard Codes	T+
RIDADR	UN 2811 6.1 / PGIII

Name: SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response f...
Source: ChEMBL
Target: Replicase polyprotein 1ab
External Id: CHEMBL4495582

Name: Antiangiogenic activity in zebrafish embryos assessed as inhibition of intersegmental...
Source: ChEMBL
Target: Danio rerio
External Id: CHEMBL2186454

Name: Antiangiogenic activity in HUVEC assessed as inhibition of tube formation at 10 uM
Source: ChEMBL
Target: HUVEC
External Id: CHEMBL2186455

Name: Antitumor activity against human SW620 cells xenografted mouse assessed as inhibition...
Source: ChEMBL
Target: SW-620
External Id: CHEMBL2186453

Name: Enzymatic assay of human HDAC6 with commercial peptide substrate
Source: ChEMBL
Target: Histone deacetylase 6
External Id: CHEMBL4808149

Name: Antitumor activity against human HepG2 cells xenografted mouse assessed as inhibition...
Source: ChEMBL
Target: HepG2
External Id: CHEMBL2185929

Name: Enzymatic assay of human HDAC6 with custom peptide substrate
Source: ChEMBL
Target: Histone deacetylase 6
External Id: CHEMBL4808150

Name: Primary qHTS for inhibitors of NSP2Pro chikungunya virus (CHIKV)
Source: NCGC
External Id: APP-Toga-CHIKV-nsp2-p

Name: Primary qHTS Assay for Inhibitors of Recombinant Selenoprotein Glutathione Peroxidase...
Source: NCGC
External Id: GPx1-biochemical-p4-p7

Name: Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: HCMV UL50
External Id: HMS1262

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SKLB1002-25mg

6,7-Dimethoxy-4-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]quinazoline

SKLB1002

S7258

SKLB1002-10mg

SKLB1002-5mg

SKLB1002-50mg

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: SKLB1002
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Amole Biotechnology Co., Ltd.
China
Product Name: SKLB1002
Price: ￥Inquiry/100mg ￥Inquiry/10mg ￥Inquiry/1g ￥Inquiry/250mg
Purity: 99.0%
Delivery: Inquiry
Contact: Xiyao Wang
Email: 3623107365@qq.com

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SKLB1002

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.