Zotarolimus
Modify Date: 2025-08-23 10:56:45
Zotarolimus structure
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Common Name | Zotarolimus | ||
|---|---|---|---|---|
| CAS Number | 221877-54-9 | Molecular Weight | 966.210 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 1016.2±75.0 °C at 760 mmHg | |
| Molecular Formula | C52H79N5O12 | Melting Point | 100-105°C | |
| MSDS | N/A | Flash Point | 568.4±37.1 °C | |
Use of ZotarolimusZotarolimus is a tetrazole-containing Rapamycin analog which is used as animmunomodulator, and is useful in the treatment of restenosis, immune, and autoimmune diseases. |
| Name | Zotarolimus |
|---|---|
| Synonym | More Synonyms |
| Description | Zotarolimus is a tetrazole-containing Rapamycin analog which is used as animmunomodulator, and is useful in the treatment of restenosis, immune, and autoimmune diseases. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 1016.2±75.0 °C at 760 mmHg |
| Melting Point | 100-105°C |
| Molecular Formula | C52H79N5O12 |
| Molecular Weight | 966.210 |
| Flash Point | 568.4±37.1 °C |
| Exact Mass | 965.572510 |
| PSA | 218.80000 |
| LogP | 3.55 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.586 |
| InChIKey | CGTADGCBEXYWNE-VNODUHINSA-N |
| SMILES | COC1CC2CCC(C)C(O)(O2)C(=O)C(=O)N2CCCCC2C(=O)OC(C(C)CC2CCC(n3cnnn3)C(OC)C2)CC(=O)C(C)C=C(C)C(O)C(OC)C(=O)C(C)CC(C)C=CC=CC=C1C |
| Storage condition | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
| HS Code | 29349990 |
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Name: Primary qHTS assay for small molecule inhibitors of Inositol hexaphosphate kinase 1 (...
Source: NCGC
External Id: IP6K1-p1
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Name: Human FK506 binding protein 1A (5.2.-.- Cis-trans-isomerases)
Source: IUPHAR-DB
Target: FK506 binding protein 1A (5.2.-.- Cis-trans-isomerases) [Homo sapiens]
External Id: 2609_Human
|
|
Name: SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response f...
Source: ChEMBL
Target: Replicase polyprotein 1ab
External Id: CHEMBL4495582
|
|
Name: Antiviral activity against SARS-CoV-2 (USA-WA1/2020 strain) measured by imaging in HR...
Source: ChEMBL
Target: Severe acute respiratory syndrome coronavirus 2
External Id: CHEMBL4303810
|
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Name: Apparent terminal half life in Sprague-Dawley rat at 2.5 mg/kg, po administered via g...
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL4258272
|
|
Name: Apparent terminal half life in Sprague-Dawley rat at 2.5 mg/kg, iv administered as bo...
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL4258271
|
|
Name: Enzymatic assay of human HDAC6 with commercial peptide substrate
Source: ChEMBL
Target: Histone deacetylase 6
External Id: CHEMBL4808149
|
|
Name: Enzymatic assay of human HDAC6 with custom peptide substrate
Source: ChEMBL
Target: Histone deacetylase 6
External Id: CHEMBL4808150
|
|
Name: Primary qHTS for inhibitors of NSP2Pro chikungunya virus (CHIKV)
Source: NCGC
External Id: APP-Toga-CHIKV-nsp2-p
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|
Name: Inhibition of N-terminal GST-tagged recombinant human MKK3 S198E/T193E mutant express...
Source: ChEMBL
Target: N/A
External Id: CHEMBL5550262
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| (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-19,30-dimethoxy-12-{(2R)-1-[(1S,3R,4S)-3-methoxy-4-(1H-tetrazol-1-yl)cyclohexyl]-2-propanyl}-15,17,21,23,29,35-hexamethyl-11, ;36-dioxa-4-azatricyclo[30.3.1.0]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone |
| (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-10,21-dimethoxy-3-{(2R)-1-[(1S,3R,4S)-3-methoxy-4-(1H-tetrazol-1-yl)cyclohexyl]propan-2-yl}-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone |
| Zotarolimus |
| ABT-578 |