Ceftazidime Pentahydrate

Modify Date: 2025-08-23 11:57:47

Ceftazidime Pentahydrate Structure
Ceftazidime Pentahydrate structure
Common Name Ceftazidime Pentahydrate
CAS Number 78439-06-2 Molecular Weight 546.576
Density N/A Boiling Point N/A
Molecular Formula C22H32N6O12S2 Melting Point >150ºC(dec.)
MSDS N/A Flash Point N/A

 Use of Ceftazidime Pentahydrate


Ceftazidime pentahydrate (GR20263 pentahydrate) is a third generation cephalosporin administered intravenously or intramuscularly. Ceftazidime pentahydrate has a broad spectrum of in vitro activity against Gram-positive and Gram-negative aerobic bacteria. Ceftazidime pentahydrate is particularly active against Enterobacteriaceae (including beta-lactamase-positive strains) and is resistant to hydrolysis by most beta-lactamases[1].

 Names

Name ceftazidime pentahydrate
Synonym More Synonyms

 Ceftazidime Pentahydrate Biological Activity

Description Ceftazidime pentahydrate (GR20263 pentahydrate) is a third generation cephalosporin administered intravenously or intramuscularly. Ceftazidime pentahydrate has a broad spectrum of in vitro activity against Gram-positive and Gram-negative aerobic bacteria. Ceftazidime pentahydrate is particularly active against Enterobacteriaceae (including beta-lactamase-positive strains) and is resistant to hydrolysis by most beta-lactamases[1].
Related Catalog
References

[1]. Richards DM, et al. Ceftazidime. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use. Drugs. 1985 Feb;29(2):105-61.

 Chemical & Physical Properties

Melting Point >150ºC(dec.)
Molecular Formula C22H32N6O12S2
Molecular Weight 546.576
Exact Mass 546.099121
PSA 244.76000
LogP -2.84
InChIKey NMVPEQXCMGEDNH-TZVUEUGBSA-N
SMILES CC(C)(ON=C(C(=O)NC1C(=O)N2C(C(=O)[O-])=C(C[n+]3ccccc3)CSC12)c1csc(N)n1)C(=O)[O-].O.O.O.O.O.[H+]
Storage condition 2-8°C

 Safety Information

Hazard Codes Xn: Harmful;
Risk Phrases R42/43
Safety Phrases 22-36/37-45-37-24
RIDADR NONH for all modes of transport
WGK Germany 1
HS Code 2941905990

 Customs

HS Code 2941905990

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 Ceftazidime PentahydrateBioassay

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Name: qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signa...
Source: 824
Target: AR protein [Homo sapiens]
External Id: MDAN535
Name: qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
Source: NCGC
Target: TDP1 protein [Homo sapiens]
External Id: TDP1100
Name: qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
Source: NCGC
Target: TDP1 protein [Homo sapiens]
External Id: TDP1101
Name: qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cel...
Source: 824
Target: RecName: Full=ATPase family AAA domain-containing protein 5; AltName: Full=Chromosome fragility-associated gene 1 protein
External Id: ELG271
Name: qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen1, green ...
Source: NCGC
Target: N/A
External Id: Ebola screen1_EM141217_green
Name: qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signal...
Source: 824
Target: thyroid hormone receptor beta isoform 2 [Rattus norvegicus]
External Id: TRN186
Name: Dicer-mediated maturation of pre-microRNA
Source: Center for Chemical Genomics, University of Michigan
Target: N/A
External Id: TargetID_659_CEMA
Name: qHTS Assay for Identifying Compounds that block Entry of Ebola Virus: Screen1, ratio ...
Source: NCGC
Target: N/A
External Id: Ebola screen1_EM141217_ratio
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 Synonyms

MFCD00153936
EINECS 276-715-9
Pyridinium, 1-[[(6R,7R)-7-[[2-(2-amino-4-thiazolyl)-2-[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, inner salt
(6R,7R)-7-{[(2-Amino-1,3-thiazol-4-yl){[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
(6R,7R)-7-{[(2-Amino-1,3-thiazol-4-yl){[(2-carboxy-2-propanyl)oxy]imino}acetyl]amino}-8-oxo-3-(1-pyridiniumylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
Ceftazidime
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