2-Amino-6-chlorobenzimidazole

Modify Date: 2026-07-10 09:52:12

2-Amino-6-chlorobenzimidazole Structure
2-Amino-6-chlorobenzimidazole structure
Common Name 2-Amino-6-chlorobenzimidazole
CAS Number 5418-93-9 Molecular Weight 167.596
Density 1.5±0.1 g/cm3 Boiling Point 402.5±37.0 °C at 760 mmHg
Molecular Formula C7H6ClN3 Melting Point N/A
MSDS N/A Flash Point 197.3±26.5 °C

 Names

Name 2-Amino-6-chlorobenzimidazole
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 402.5±37.0 °C at 760 mmHg
Molecular Formula C7H6ClN3
Molecular Weight 167.596
Flash Point 197.3±26.5 °C
Exact Mass 167.025024
PSA 54.70000
LogP 1.88
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.777
InChIKey PDOCNPCPPLPXRV-UHFFFAOYSA-N
SMILES Nc1nc2ccc(Cl)cc2[nH]1

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DD6200500
CHEMICAL NAME :
Benzimidazole, 2-amino-5-chloro-
CAS REGISTRY NUMBER :
5418-93-9
LAST UPDATED :
199701
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C7-H6-Cl-N3
MOLECULAR WEIGHT :
167.61
WISWESSER LINE NOTATION :
T56 BM DNJ CZ HG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
112 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#12521

 Safety Information

HS Code 2933990090

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 2-Amino-6-chlorobenzimidazoleBioassay

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Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
Name: The compound was tested in vitro against the protozoa Giardia lamblia, for the inhibi...
Source: ChEMBL
Target: Giardia intestinalis
External Id: CHEMBL682614
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
Name: Primary Screen Inhibitors of CD40 Signaling in BL2 Cells Measured in Cell-Based Syste...
Source: Broad Institute
Target: N/A
External Id: 7124-01_Inhibitor_SinglePoint_HTS_Activity
Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id: SIAE_INH_FP_1536_1X%INH PRUN
Name: PTR1 Activity Assay from Article 10.1021/jm900414x: "One scaffold, three binding mode...
Source: BindingDB
Target: N/A
External Id: BindingDB_3356_1
Name: uHTS identification of small molecule modulators of NR3A
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: SBCCG-A1015-NR3A-Primary-Assay
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 Synonyms

6-chloro-1H-benzimidazol-2-amine
2-Amino-6-chlorobenzimidazole
MFCD08234599
5-Chloro-1H-benzimidazol-2-amine
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