10.1038/ncb3579

2017-07-17

In this Review, Prinz and co-authors discuss the role of the endoplasmic reticulum (ER) in the de novo generation of peroxisomes, lipid droplets and omegasomes, and how this requires subdomains with specific protein and lipid compositions.

10.1038/ncb3574

2017-07-17

Pitulescu et al. and Hasan et al. show that Dll4–Notch signalling in endothelial tip cells regulates angiogenesis through control of artery formation, linking sprouting angiogenesis and artery formation.

10.1038/ncb3576

2017-07-17

Lengefeld et al. reveal how yeast cells distinguish between newly synthesized and pre-existing spindle pole bodies to enable their asymmetric segregation, through a mechanism involving Swe1, Kin3 and NuA4.

10.1038/ncb3555

2017-07-17

Pitulescu et al. show that Dll4–Notch signalling induces a cell fate switch to specify future arterial endothelial cells among the progeny of tip cells, linking sprouting angiogenesis and artery formation.

10.1038/ncb3570

2017-07-17

Zhou et al. demonstrate that bone marrow adipocytes, but not intraperitoneal adipocytes, express high levels of stem cell factor (SCF), which is essential for the regeneration of haematopoietic stem cells and haematopoiesis after irradiation.

10.1038/ncb3571

2017-06-29

The Nature journals' recently updated reporting requirements for life sciences aim to enhance the quality and transparency of methodological and experimental reporting.

10.1038/ncb3567

2017-06-29

Several markers of gastric stem cells have been identified in recent years. Now a study demonstrates that Lgr5 marks a population of reserve stem cells located at the base of the corpus glands of the gastric epithelium, and that these cells can also act as a ...

10.1038/ncb3569

2017-06-29

The endosomal sorting complex required for transport (ESCRT)-III is critical for membrane abscission; however, the mechanism underlying ESCRT-III-mediated membrane constriction remains elusive. A study of the dynamic assembly and disassembly of the ESCRT-III ...

10.1038/ncb3568

2017-06-29

Haem is an iron-containing cofactor required for life. Many cellular processes rely on haem and failure to maintain iron homeostasis results in numerous pathological conditions. A study now identifies a Caenorhabditis elegans inter-organ signalling pathway in...

10.1038/ncb3566

2017-06-29

The mechanism of action of oncogenes in acute myeloid leukaemia is poorly understood. A study now shows that the fusion oncoprotein AML1-ETO regulates leukaemogenesis by increasing the expression of small nucleolar RNAs through post-transcriptional mechanisms...