Effect of n-alkanes on lipid bilayers depending on headgroups.

Chem. Phys. Lipids 188 , 61-7, (2015)

2015-05-01

Phase behavior and structural properties were examined for phospholipid bilayers having different headgroups (DMPC, DMPS and DMPE) with added n-alkanes to study effect of flexible additives. Change in the temperatures of main transition of the lipid/alkane mi...

Dietary docosahexaenoic acid supplementation reduces SERCA Ca2+ transport efficiency in rat skeletal muscle.

Chem. Phys. Lipids 187 , 56-61, (2015)

2015-04-01

Docosahexaenoic acid (DHA) can reduce the efficiency and increase the energy consumption of Na(+)/K(+)-ATPase pump and mitochondrial electron transport chain by promoting Na(+) and H(+) membrane permeability, respectively. In skeletal muscle, the sarco(endo) ...

NMR-based molecular ruler for determining the depth of intercalants within the lipid bilayer. Part V: a comparison of liposomes, bioliposomes and erythrocyte ghosts.

Chem. Phys. Lipids 184 , 52-60, (2014)

2014-12-01

Afri et al. (2014a,b) have recently reported their mapping of DMPC liposomes using (13)C NMR in conjunction with a wide range of difunctional intercalants: n-ketoesters, n-ketoacids and n-ketophosphatidylcholines. The present study initiates a comparable stud...

NMR-based molecular ruler for determining the depth of intercalants within the lipid bilayer. Part IV: studies on ketophospholipids.

Chem. Phys. Lipids 184 , 119-28, (2014)

2014-12-01

In our companion paper, we described the preparation and intercalation of two homologous series of dicarbonyl compounds, methyl n-oxooctadecanoates and the corresponding n-oxooctadecanoic acids (n=4-16), into DMPC liposomes. (13)C NMR chemical shift of the va...

Partitioning of ethanol in multi-component membranes: effects on membrane structure.

Chem. Phys. Lipids 166 , 1-11, (2013)

2013-01-01

The molecular mechanism of ethanol and its effects on neurological function is far from clear. In this study, we investigate the effects of ethanol on various structural and dynamical properties of mixed bilayers consisting of different ratios of dipalmitoylp...

Halogenated phospholipids regulate secretory phospholipase A2 group IIA activity.

Chem. Phys. Lipids 167-168 , 51-6, (2013)

2013-01-01

Secretory phospholipase A2 group IIA (sPLA2-IIA) is an active participant of inflammation. The enzyme destroys bacterial cell wall and induces production of biologically active lipid mediators. It is involved in various pathological processes and high serum c...

Adsorption of the antimicrobial peptide arenicin and its linear derivative to model membranes--a maximum insertion pressure study.

Chem. Phys. Lipids 167-168 , 43-50, (2013)

2013-01-01

Antimicrobial peptides (AMPs) are widely distributed in nature representing an ancient tool of host defence against bacterial invasion. The ability of the cyclic cationic antimicrobial peptide arenicin, Ar-1, and its novel and highly efficient linear derivati...

A highly sensitive quantification of phytosterols through an inexpensive derivatization.

Chem. Phys. Lipids 166 , 18-25, (2013)

2013-01-01

A highly sensitive method for quantification of phytosterols based on HPLC has been developed by derivatization with the benzoyl chromophore. Introduction of the chromophore, benzoyl group, to phytosterols via simple and inexpensive derivatization greatly imp...

The onset of Triton X-100 solubilization of sphingomyelin/ceramide bilayers: effects of temperature and composition.

Chem. Phys. Lipids 167-168 , 57-61, (2013)

2013-01-01

The early stages of Triton X-100 solubilization of bilayers consisting of sphingomyelin/ceramide (SM/Cer) mixtures have been studied using a combination of calorimetric and spectroscopic techniques. Compositions based on sphingomyelin, containing up to 30 mol...

Visualizing a multidrug resistance protein, EmrE, with major bacterial lipids using Brewster angle microscopy.

Chem. Phys. Lipids 167-168 , 33-42, (2013)

2013-01-01

Understanding lipid-protein interactions to enhance our knowledge of membrane architecture is a critical step in the development of novel therapeutic measures to respond to the drastic rise of drug resistant microorganisms. Escherichia coli contains a small a...