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Design of Rigid Cyclic Tripyrrins: The Importance of Intermolecular Interactions on Aggregation and Luminescence
10.1039/C8QO00313K 2018-04-11 We designed a cyclic tripyrrin “locked” by a bridging benzene-1,4-diol moiety which is perpendicular to tripyrrin plane. The cyclic structures promote the scaffold rigidity and enhances the fluorescence. While the halogen-substitution of bridging moiety was f... |
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Enantioselective indium(I)-catalyzed [4 + 2] annulation of alkoxyallenes and β,γ-unsaturated α-keto esters
10.1039/C8QO00319J 2018-04-09 An indium(I)–chiral phosphoric acid complex was found to catalyze the enantioselective [4 + 2] annulation reaction of β,γ-unsaturated α-keto esters with alkoxyallenes, affording cyclic O,O-acetals in good yields and with high regio- and stereo-selectivities. |
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Controllable synthetic ion channels
10.1039/C8QO00287H 2018-04-09 Natural channel proteins are complex in structure and marvelous in function. Chemists have constructed a variety of simple synthetic structures with the goal of mimicking the function of channel proteins. The objective of this review is to recall the developm... |
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Total synthesis of (±)-(1β,4β,4aβ,8aα)-4,8a-dimethyl-octahydro-naphthalene-1,4a(2H)-diol
10.1039/C8QO00225H 2018-04-04 The first total synthesis of (±)-(1β,4β,4aβ,8aα)-4,8a-dimethylocta-hydronaphthalene-1,4a(2H)-diol (1), a degraded sesquiterpene isolated from a fermentation broth of Streptomyces albolongus, has been achieved via three different synthetic approaches (13–15 st... |
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α,β-Diaryl unsaturated ketones via palladium-catalyzed ring-opening of cyclopropenones with organoboronic acids
10.1039/C8QO00241J 2018-04-04 Palladium-catalyzed ring-opening acylation of cyclopropenones with organoboronic acids at room temperature has been developed. Both arylboronic acids and vinylboronic acids are viable in this acylation reaction, providing a new protocol to synthesise α,β-diar... |
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The stabilizing effect of the transient imine directing group in the Pd(II)-catalyzed C(sp3)–H arylation of free primary amines
10.1039/C8QO00094H 2018-04-02 A transient directing group (DG) has been successfully applied to assist the activation of C–H bonds. In this paper, we have performed density functional theory (DFT) calculations to investigate the mechanism of ligand-assisted Pd(II)-catalyzed C(sp3)–H aryla... |
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Decarboxylative formylation of aryl halides with glyoxylic acid by merging organophotoredox with palladium catalysis
10.1039/C8QO00253C 2018-04-02 Decarboxylative formylation of aryl and heteroaryl halides with glyoxylic acid is enabled by synergistic catalysis using an organic dye, 2,4,5,6-tetra(9H-carbazol-9-yl)isophthalonitrile (4CzIPN), and a phosphine ligated palladium catalyst under mild irradiati... |
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Lithocarpins A–D: four tenellone-macrolide conjugated [4 + 2] hetero-adducts from the deep-sea derived fungus Phomopsis lithocarpus FS508
10.1039/C8QO00095F 2018-04-02 Lithocarpins A–D (1–4), the first examples of highly oxygenated tenellone-macrolide conjugated dimers, were isolated from the deep-sea derived fungus Phomopsis lithocarpus FS508. Their structures were elucidated by extensive spectroscopic analyses and X-ray d... |
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Metal-free aerobic oxidative direct C–H amination of electron-deficient alkenes via photoredox catalysis
10.1039/C8QO00161H 2018-04-02 The first example of photocatalytic dehydrogenative cross-coupling of electron-poor alkenes with azoles has been reported. This method provides a novel approach for N-vinylazole synthesis, which enables coupling of a broad scope of azoles and electron-deficie... |
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Directing group assisted ZnI2-catalyzed cyclopropanation of indoles via 2-furylcarbenoids
10.1039/C8QO00232K 2018-03-30 A directing group promoting the cyclopropanation of indoles with 2-furylcarbenoids has been developed. These carbenes are derived from enynones and cost-effective ZnI2 is employed as the catalyst for the efficient construction of various polycyclic compounds ... |