Amylin (20-29) (human)

Modify Date: 2024-01-10 19:41:50

Amylin (20-29) (human) structure	Common Name	Amylin (20-29) (human)
	CAS Number	118068-30-7	Molecular Weight	1009.07
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₃H₆₈N₁₂O₁₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Amylin (20-29) (human)

Amylin (20-29) (human) is the fragment of human islet amyloid polypeptide (hIAPP) or Amylin. Amylin is a 37-residue hormone. Amylin (20-29) (human) is responsible for the amyloidogenic propensities of the full length protein. Amylin (20-29) (human) can be transformed into its corresponding peptoid and retropeptoid sequences, to obtain beta-sheet breaker peptides as amyloid inhibitors[1][2].

Name	h-ser-asn-asn-phe-gly-ala-ile-leu-ser-ser-oh
Synonym	More Synonyms

Description	Amylin (20-29) (human) is the fragment of human islet amyloid polypeptide (hIAPP) or Amylin. Amylin is a 37-residue hormone. Amylin (20-29) (human) is responsible for the amyloidogenic propensities of the full length protein. Amylin (20-29) (human) can be transformed into its corresponding peptoid and retropeptoid sequences, to obtain beta-sheet breaker peptides as amyloid inhibitors[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
References	[1]. Kapurniotu A, et al. Structure-based design and study of non-amyloidogenic, double N-methylated IAPP amyloid core sequences as inhibitors of IAPP amyloid formation and cytotoxicity. J Mol Biol. 2002 Jan 18;315(3):339-50. [2]. Elgersma RC, et al. Transformation of the amyloidogenic peptide amylin(20-29) into its corresponding peptoid and retropeptoid: access to both an amyloid inhibitor and template for self-assembled supramolecular tapes. Bioorg Med Chem Lett. 2007 Apr 1;17(7):1837-42.

Description

Related Catalog

Signaling Pathways >> Others >> Others

Research Areas >> Neurological Disease

References

[1]. Kapurniotu A, et al. Structure-based design and study of non-amyloidogenic, double N-methylated IAPP amyloid core sequences as inhibitors of IAPP amyloid formation and cytotoxicity. J Mol Biol. 2002 Jan 18;315(3):339-50.

[2]. Elgersma RC, et al. Transformation of the amyloidogenic peptide amylin(20-29) into its corresponding peptoid and retropeptoid: access to both an amyloid inhibitor and template for self-assembled supramolecular tapes. Bioorg Med Chem Lett. 2007 Apr 1;17(7):1837-42.

Molecular Formula	C₄₃H₆₈N₁₂O₁₆
Molecular Weight	1009.07
Exact Mass	1008.49000
PSA	472.09000

Safety Phrases	22-24/25
WGK Germany	3

AMYLIN FRAGMENT 20-29 HUMAN

SER-ASN-ASN-PHE-GLY-ALA-ILE-LEU-SER-SER

diabetes associated peptide fragment 20-29 human

SNNFGAILSS

Amylin (20-29) (human)

Use of Amylin (20-29) (human)

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