PKR-IN-C51

Modify Date: 2024-01-06 18:04:34

PKR-IN-C51 structure	Common Name	PKR-IN-C51
	CAS Number	1314594-23-4	Molecular Weight	367.45
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₂₁N₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PKR-IN-C51

PKR-IN-C51(compound 51) is an ATP-competitive double-stranded RNA-activated protein kinase (PKR) inhibitor with an IC50 of 9 μM. PKR-IN-C51 inhibits intracellular PKR activation in a dose-dependent manner in primary mouse macrophages[1].

Name	PKR-IN-C51

Description	PKR-IN-C51(compound 51) is an ATP-competitive double-stranded RNA-activated protein kinase (PKR) inhibitor with an IC50 of 9 μM. PKR-IN-C51 inhibits intracellular PKR activation in a dose-dependent manner in primary mouse macrophages[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Ser/Thr Protease Research Areas >> Infection
Target	IC50: 9 μM (double-stranded RNA-activated protein kinase (PKR))[1]
References	[1]. Ruslana Bryk, et al. Identification of new inhibitors of protein kinase R guided by statistical modeling. Bioorg Med Chem Lett. 2011 Jul 1;21(13):4108-14.

Molecular Formula	C₂₃H₂₁N₅
Molecular Weight	367.45

PKR-IN-C51

Use of PKR-IN-C51

Names

PKR-IN-C51 Biological Activity

Chemical & Physical Properties