PKR-IN-C51

Modify Date: 2024-01-06 18:04:34

PKR-IN-C51 Structure
PKR-IN-C51 structure
Common Name PKR-IN-C51
CAS Number 1314594-23-4 Molecular Weight 367.45
Density N/A Boiling Point N/A
Molecular Formula C23H21N5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PKR-IN-C51


PKR-IN-C51(compound 51) is an ATP-competitive double-stranded RNA-activated protein kinase (PKR) inhibitor with an IC50 of 9 μM. PKR-IN-C51 inhibits intracellular PKR activation in a dose-dependent manner in primary mouse macrophages[1].

 Names

Name PKR-IN-C51

 PKR-IN-C51 Biological Activity

Description PKR-IN-C51(compound 51) is an ATP-competitive double-stranded RNA-activated protein kinase (PKR) inhibitor with an IC50 of 9 μM. PKR-IN-C51 inhibits intracellular PKR activation in a dose-dependent manner in primary mouse macrophages[1].
Related Catalog
Target

IC50: 9 μM (double-stranded RNA-activated protein kinase (PKR))[1]

References

[1]. Ruslana Bryk, et al. Identification of new inhibitors of protein kinase R guided by statistical modeling. Bioorg Med Chem Lett. 2011 Jul 1;21(13):4108-14.

 Chemical & Physical Properties

Molecular Formula C23H21N5
Molecular Weight 367.45
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