guvacine hydrobromide
Modify Date: 2024-04-06 12:46:34
guvacine hydrobromide structure
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Common Name | guvacine hydrobromide | ||
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| CAS Number | 6027-92-5 | Molecular Weight | 208.05 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C6H10BrNO2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of guvacine hydrobromideGuvacine hydrobromide, an alkaloid found in the nut of Areca catechu, is a potent GABA uptakp inhibitor. Guvacine hydrobromide inhibits rat GAT-1, rat GAT-2 and rat GAT-3 with IC50 values of 39 μM, 58 μM and 378 μM, respectively[1]. |
| Name | guvacine hydrobromide |
|---|---|
| Synonym | More Synonyms |
| Description | Guvacine hydrobromide, an alkaloid found in the nut of Areca catechu, is a potent GABA uptakp inhibitor. Guvacine hydrobromide inhibits rat GAT-1, rat GAT-2 and rat GAT-3 with IC50 values of 39 μM, 58 μM and 378 μM, respectively[1]. |
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| Related Catalog | |
| Target |
IC50: 39 μM (rat GAT-1), 58 μM (rat GAT-2), 378 μM (rat GAT-3), 14 μM (human GAT-1), 119 μM (huam GAT-3) and 1870 μM (human BGT-3)[1] |
| References |
| Molecular Formula | C6H10BrNO2 |
|---|---|
| Molecular Weight | 208.05 |
| Exact Mass | 206.98900 |
| PSA | 49.33000 |
| LogP | 1.27760 |
| Precursor 0 | |
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| DownStream 2 | |
CAS#:86447-11-2
CAS#:163438-09-3| 1,2,5,6-tetrahydro-pyridine-3-carboxylic acid , hydrobromide |
| 1,2,5,6-Tetrahydro-pyridin-3-carbonsaeure, Hydrobromid |