Guvacine hydrobromide

Modify Date: 2026-07-16 16:56:29

Guvacine hydrobromide Structure
Guvacine hydrobromide structure
Common Name Guvacine hydrobromide
CAS Number 6027-92-5 Molecular Weight 208.05
Density N/A Boiling Point N/A
Molecular Formula C6H10BrNO2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Guvacine hydrobromide


Guvacine hydrobromide, an alkaloid found in the nut of Areca catechu, is a potent GABA uptakp inhibitor. Guvacine hydrobromide inhibits rat GAT-1, rat GAT-2 and rat GAT-3 with IC50 values of 39 μM, 58 μM and 378 μM, respectively[1].

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name guvacine hydrobromide
Synonym More Synonyms

 Guvacine hydrobromide Biological Activity

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description Guvacine hydrobromide, an alkaloid found in the nut of Areca catechu, is a potent GABA uptakp inhibitor. Guvacine hydrobromide inhibits rat GAT-1, rat GAT-2 and rat GAT-3 with IC50 values of 39 μM, 58 μM and 378 μM, respectively[1].
Related Catalog
Target

IC50: 39 μM (rat GAT-1), 58 μM (rat GAT-2), 378 μM (rat GAT-3), 14 μM (human GAT-1), 119 μM (huam GAT-3) and 1870 μM (human BGT-3)[1]

References

[1]. L A Borden, et al. Tiagabine, SK&F 89976-A, CI-966, and NNC-711 are selective for the cloned GABA transporter GAT-1. Eur J Pharmacol. 1994 Oct 14;269(2):219-24.  

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Molecular Formula C6H10BrNO2
Molecular Weight 208.05
Exact Mass 206.98900
PSA 49.33000
LogP 1.27760

 Precursor & DownStream

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor  0

DownStream  2

 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

1,2,5,6-tetrahydro-pyridine-3-carboxylic acid , hydrobromide
1,2,5,6-Tetrahydro-pyridin-3-carbonsaeure, Hydrobromid

 Guvacine hydrobromide | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the polar surface area (PSA) of guvacine hydrobromide?
A: Polar surface area (PSA) of guvacine hydrobromide is 49.33000.
Q: What is the Chinese name of 6027-92-5?
A: Chinese name of 6027-92-5 is 6027-92-5.
Q: What English synonyms does guvacine hydrobromide have?
A: English synonyms of guvacine hydrobromide: 1,2,5,6-tetrahydro-pyridine-3-carboxylic acid , hydrobromide, 1,2,5,6-Tetrahydro-pyridin-3-carbonsaeure, Hydrobromid.
Q: What are the uses of guvacine hydrobromide?
A: Main uses of guvacine hydrobromide: Guvacine hydrobromide, an alkaloid found in the nut of Areca catechu, is a potent GABA uptakp inhibitor. Guvacine hydrobromide inhibits rat GAT-1, rat GAT-2 and rat GAT-3 with IC50 values of 39 μM, 58 μM and 378 μM, respectively[1].
Q: What are the downstream products of guvacine hydrobromide?
A: Related downstream products(CAS) of guvacine hydrobromide: 86447-11-2;163438-09-3.
Q: What is the LogP of guvacine hydrobromide?
A: LogP of guvacine hydrobromide is 1.27760.
Q: What is the CAS number of guvacine hydrobromide?
A: CAS number of guvacine hydrobromide is 6027-92-5.
Q: What is the English name of guvacine hydrobromide?
A: The English name of guvacine hydrobromide is guvacine hydrobromide.
Q: What is the molecular formula of guvacine hydrobromide?
A: Molecular formula of guvacine hydrobromide is C6H10BrNO2.
Q: What is the molecular weight of guvacine hydrobromide?
A: Molecular weight of guvacine hydrobromide is 208.05.

 Guvacine hydrobromidefactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
naturewill
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