Guvacine hydrobromide

Modify Date: 2025-09-26 14:15:09

Guvacine hydrobromide structure	Common Name	Guvacine hydrobromide
	CAS Number	6027-92-5	Molecular Weight	208.05
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₆H₁₀BrNO₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Guvacine hydrobromide

Guvacine hydrobromide, an alkaloid found in the nut of Areca catechu, is a potent GABA uptakp inhibitor. Guvacine hydrobromide inhibits rat GAT-1, rat GAT-2 and rat GAT-3 with IC50 values of 39 μM, 58 μM and 378 μM, respectively[1].

Name	guvacine hydrobromide
Synonym	More Synonyms

Description	Guvacine hydrobromide, an alkaloid found in the nut of Areca catechu, is a potent GABA uptakp inhibitor. Guvacine hydrobromide inhibits rat GAT-1, rat GAT-2 and rat GAT-3 with IC50 values of 39 μM, 58 μM and 378 μM, respectively[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> GABA Receptor
Target	IC50: 39 μM (rat GAT-1), 58 μM (rat GAT-2), 378 μM (rat GAT-3), 14 μM (human GAT-1), 119 μM (huam GAT-3) and 1870 μM (human BGT-3)[1]
References	[1]. L A Borden, et al. Tiagabine, SK&F 89976-A, CI-966, and NNC-711 are selective for the cloned GABA transporter GAT-1. Eur J Pharmacol. 1994 Oct 14;269(2):219-24.

Molecular Formula	C₆H₁₀BrNO₂
Molecular Weight	208.05
Exact Mass	206.98900
PSA	49.33000
LogP	1.27760

Precursor 0
DownStream 2
CAS#:86447-11-2 1-Boc-1,2,5,6-t... CAS#:163438-09-3 (R)-Boc-Nipecot...

1,2,5,6-tetrahydro-pyridine-3-carboxylic acid , hydrobromide

1,2,5,6-Tetrahydro-pyridin-3-carbonsaeure, Hydrobromid

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Guvacine hydrobromide
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Guvacine hydrobromide
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Delivery: 10 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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