O-Desmethyl Midostaurin structure
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Common Name | O-Desmethyl Midostaurin | ||
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CAS Number | 740816-86-8 | Molecular Weight | 556.61 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C34H28N4O4 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of O-Desmethyl MidostaurinO-Desmethyl Midostaurin (CGP62221; O-Desmethyl PKC412) is the active metabolite of Midostaurin (HY-10230) via cytochrome P450 liver enzyme metabolism. O-Desmethyl Midostaurin can be used as an indicator for Midostaurin metabolism in vivo[1]. Midostaurin is a multi-targeted protein kinase inhibitor with IC50 ranging from 22-500 nM. |
Name | O-Desmethyl Midostaurin |
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Description | O-Desmethyl Midostaurin (CGP62221; O-Desmethyl PKC412) is the active metabolite of Midostaurin (HY-10230) via cytochrome P450 liver enzyme metabolism. O-Desmethyl Midostaurin can be used as an indicator for Midostaurin metabolism in vivo[1]. Midostaurin is a multi-targeted protein kinase inhibitor with IC50 ranging from 22-500 nM. |
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Related Catalog | |
Target |
IC50: active metabolite of Midostaurin[1] |
References |
Molecular Formula | C34H28N4O4 |
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Molecular Weight | 556.61 |
Storage condition | -20°C |