ALR-27
Modify Date: 2024-01-12 10:26:11
ALR-27 structure
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Common Name | ALR-27 | ||
|---|---|---|---|---|
| CAS Number | 903639-13-4 | Molecular Weight | 298.38 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H22O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of ALR-27ALR-27 is an antagonist of the 5-lipoxygenase (5-LOX) activating protein FLAP and has anti-inflammatory activity. ALR-27 potently inhibits 5-LOX product formation (>80%) in pro-inflammatory M1-MDM, with no significant direct inhibition of 5-LOX. ALR-27 not only reduces prostaglandin and leukotriene (LT) production in neutrophils but also increases the production of specialized prolytic mediators in specific human macrophage phenotypes[1]. |
| Name | ALR-27 |
|---|
| Description | ALR-27 is an antagonist of the 5-lipoxygenase (5-LOX) activating protein FLAP and has anti-inflammatory activity. ALR-27 potently inhibits 5-LOX product formation (>80%) in pro-inflammatory M1-MDM, with no significant direct inhibition of 5-LOX. ALR-27 not only reduces prostaglandin and leukotriene (LT) production in neutrophils but also increases the production of specialized prolytic mediators in specific human macrophage phenotypes[1]. |
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| Related Catalog | |
| Target |
FLAP[1] |
| References |
| Molecular Formula | C19H22O3 |
|---|---|
| Molecular Weight | 298.38 |