8-Aminooctanoic acid

Names

[ Name ]:
8-Aminooctanoic acid

[Synonym ]:
8-Aminocaprylic acid
8-amino capylic acid
amino caprylic acid
8-amino-n-caprylic acid
8-amino octanoic acid
8-Aminooctanoic acid
EINECS 213-687-9
8AC
omega-Aminocaprylic acid
Octanoic acid,8-amino
ω-aminocaprylic acid
MFCD00008245
Octanoic acid, 8-amino-
aminocaproic acid

Biological Activity

[Description]:

8-Aminooctanoic acid is an omega-amino fatty acid that is octanoic acid which carries an amino group at position 8. 8-aminooctanoic acid has a role as a human metabolite[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[References]

[1]. Guido Fries. Production of omega-aminoalkanoic acids useful as intermediates e.g. in the synthesis of peptides, comprises hydrolyzing corresponding lactam with aqueous alkali, precipitating with organic solvent and mechanical isolation of the product. DE10148682A1.

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
286.0±23.0 °C at 760 mmHg

[ Melting Point ]:
194 °C (dec.)(lit.)

[ Molecular Formula ]:
C₈H₁₇NO₂

[ Molecular Weight ]:
159.226

[ Flash Point ]:
126.8±22.6 °C

[ Exact Mass ]:
159.125931

[ PSA ]:
63.32000

[ LogP ]:
0.95

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.469

[ Storage condition ]:
Store at 0-5°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S22-S24/25-S37/39-S26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2922499990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Articles

Structure-activity relationship study on a simple cationic peptide motif for cellular delivery of antisense peptide nucleic acid.

J. Med. Chem. 48 , 6741-9, (2005)

Improving cellular uptake and biodistribution remains one of the major obstacles for a successful and broad application of peptide nucleic acids (PNAs) as antisense therapeutics. Recently, we reported...

Surface interactions of a homologous series of alpha,omega-amino acids on colloidal silver and gold.

Biospectroscopy 5(1) , 9-17, (1999)

Surface enhanced Raman spectroscopy (SERS) was used to characterize a homologous series of alpha,omega-amino acids on colloidal gold and silver. Raman and SER spectra of the alpha,omega-amino acids, N...

Covalent complexes between serum albumin and 7-hydroxycoumarin-4-acetic acid: synthesis and applications in the spectrophotometric detection of long-chain fatty acids.

Biochim. Biophys. Acta 1304(1) , 43-55, (1996)

Using a hydrophobic 8-aminooctanoic acid cross-linker, the pH-indicator dye 7-hydroxycoumarin-4-acetic acid (7-HCA) is covalently bound to bovine serum albumin (BSA) at the positions of reactive amino...

Related Compounds

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