(S)-(?)-Perillyl alcohol

Names

[ Name ]:
(S)-(?)-Perillyl alcohol

[Synonym ]:
tri-otolylboroxine
UNII:319R5C7293
Perilla alcohol
[4-(Prop-1-en-2-yl)cyclohex-1-en-1-yl]methanol
EINECS 208-639-9
p-Mentha-1,8-diene-7-ol
(-)-PERILLYL ALCOHOL
Perillic alcohol
1-Cyclohexene-1-methanol, 4-(1-methylethenyl)
L6UTJ A1Q DY1&U1
(S)-p-Mentha-1,8-dien-7-ol,(S)-4-Isopropenyl-1-cyclohexenylmethanol
Perillyl alcohol
(4-Isopropenyl-1-cyclohexen-1-yl)methanol
1-Cyclohexene-1-methanol, 4-(1-methylethenyl)-
MFCD00062995
[4-(1-Methylethenyl)-1-cyclohexen-1-yl]methanol
1,8-p-Menthadien-7-ol
p-Mentha-1,8-dien-7-ol

Biological Activity

[Description]:

(S)-(−)-Perillyl alcohol is a monoterpene found in lavender, inhibits farnesylation of Ras, upregulates the mannose-6-phosphate receptor and induces apoptosis. Anti-cancer activity[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cancer

[References]

[1]. Liston BW, et al. Perillyl alcohol as a chemopreventive agent in N-nitrosomethylbenzylamine-induced rat esophageal tumorigenesis. Cancer Res. 2003 May 15;63(10):2399-403.

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
241.2±19.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₀H₁₆O

[ Molecular Weight ]:
152.233

[ Flash Point ]:
99.6±17.8 °C

[ Exact Mass ]:
152.120117

[ PSA ]:
20.23000

[ LogP ]:
3.30

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.491

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R37/38

[ Safety Phrases ]:
26-39-36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
OS8395000

[ HS Code ]:
2906199090

Customs

[ HS Code ]: 2906199090

[ Summary ]:
2906199090. cyclanic, cyclenic or cyclotherpenic alcohols. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

Articles

Antitumorigenic effects of limonene and perillyl alcohol against pancreatic and breast cancer.

Adv. Exp. Med. Biol. 401 , 131-6, (1996)

Perillyl alcohol is a natural product from cherries and other edible plants. Perillyl alcohol and d-limonene, a closely related dietary monoterpene, have chemotherapeutic activity against pancreatic, ...

The promise of natural products for blocking early events in skin carcinogenesis.

Cancer Prev. Res. (Phila.) 3(2) , 132-5, (2010)

This perspective on Stratton et al. (beginning on p. 160), Kowalczyk et al. (beginning on p. 170), and Katiyar et al. (beginning on p. 179) highlights the common theme of translational investigation o...

Cell physiology rather than enzyme kinetics can determine the efficiency of cytochrome P450-catalyzed C-H-oxyfunctionalization.

J. Ind. Microbiol. Biotechnol. 38(9) , 1359-70, (2011)

Cell physiology is a critical factor determining the efficiency of reactions performed by microbial biocatalysts. In order to develop an efficient biotransformation procedure for the hydroxylation of ...

Related Compounds

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