4-Chlorophenylacetic acid
Names
[ CAS No. ]:
1878-66-6
[ Name ]:
4-Chlorophenylacetic acid
[Synonym ]:
EINECS 217-521-6
Acetic acid, 4-chlorophenyl-
(4-Chlorophenyl)acetic acid
4-Chlorobenzeneacetic acid
4-Chlorophenylacetic acid
2-(4-chloro-phenyl)-acetic acid
p-chlorophenylacetate
Acetic acid,(p-chlorophenyl)
4-Cl-phenylacetic acid
p-chlorophenyl acetic acid
Benzeneacetic acid,4-chloro
Benzeneacetic acid, 4-chloro-
2-(4-chlorophenyl)acetic acid
P-CHLOROPHENYLACETIC ACID
2-(p-Chlorophenyl)acetic acid
4-ClPhCH2CO2H
Acetic acid, (p-chlorophenyl)-
MFCD00004344
Biological Activity
[Description]:
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
294.1±15.0 °C at 760 mmHg
[ Melting Point ]:
102-105 °C(lit.)
[ Molecular Formula ]:
C8H7ClO2
[ Molecular Weight ]:
170.593
[ Flash Point ]:
131.7±20.4 °C
[ Exact Mass ]:
170.013458
[ PSA ]:
37.30000
[ LogP ]:
2.10
[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C
[ Index of Refraction ]:
1.570
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AG0590000
- CHEMICAL NAME :
- Acetic acid, (p-chlorophenyl)-
- CAS REGISTRY NUMBER :
- 1878-66-6
- BEILSTEIN REFERENCE NO. :
- 1072816
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C8-H7-Cl-O2
- MOLECULAR WEIGHT :
- 170.60
- WISWESSER LINE NOTATION :
- QV1R DG
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1350 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 13,286,1958
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H312 + H332
[ Precautionary Statements ]:
P280
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn: Harmful;Xi: Irritant;
[ Risk Phrases ]:
R20/21
[ Safety Phrases ]:
S36/37-S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
AG0590000
[ HS Code ]:
2916340090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2916399090
[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
J. Environ. Manage. 161 , 350-7, (2015)
Long term residues of organochlorine pesticides (OCPs) in soils are of great concerning because they seriously threaten food security and human health. This article focuses on isolation of OCP-degradi...
Degradation of 4-chlorophenylacetic acid by a Pseudomonas species.J. Bacteriol. 146(1) , 64-8, (1981)
Pseudomonas sp. strain CBS3 was able to utilize 4-chlorophenylacetic acid as the sole source of carbon and energy. When this strain was grown with 4-chlorophenylacetic acid, homoprotocatechuic acid wa...
Inhibition of estrogen-induced mammary tumor formation in MMTV-aromatase transgenic mice by 4-chlorophenylacetate.Cancer Lett. 251(2) , 302-10, (2007)
Treatment of estrogen-sensitive breast cancer with selective estrogen selective modulators (SERMs) and, more recently, aromatase inhibitors has met with wide success. However, antagonism of estrogen r...