5-Bromo-2-chloropyrimidine
Names
[ CAS No. ]:
32779-36-5
[ Name ]:
5-Bromo-2-chloropyrimidine
[Synonym ]:
T6N CNJ BG EE
5-BROMO-2-CHLOROPYRIMIDNE
Pyrimidine, 5-bromo-2-chloro-
2-chloro-5-bromopyrimidine(5-bromo-2-chloropyrimidine)
2C5BP
MAJORIMPURITYIS2,5-DIBROMOPYRIMIDINE
PYRIMIDINE,5-BROMO-2-CHLORO
5-bromo-2-chloro-pyrimidine
MFCD00483232
2-CHLORO-5-BROMOPYRIMIDINE
5-Bromo-2-chloropyrimidine
5-Bromo-2-chloro-1,3-diazine
2,5-bromochloro pyrimidine
2-chloro-5-bromopyridine
Biological Activity
[Description]:
[Related Catalog]:
[In Vitro]
Chemical & Physical Properties
[ Density]:
1.9±0.1 g/cm3
[ Boiling Point ]:
291.6±13.0 °C at 760 mmHg
[ Melting Point ]:
76-81 °C(lit.)
[ Molecular Formula ]:
C4H2BrClN2
[ Molecular Weight ]:
193.43
[ Flash Point ]:
130.1±19.8 °C
[ Exact Mass ]:
191.908981
[ PSA ]:
25.78000
[ LogP ]:
1.36
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.588
[ Water Solubility ]:
insoluble
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36/39-S37/39
[ RIDADR ]:
UN 3335
[ WGK Germany ]:
3
[ HS Code ]:
2933599090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933599090
[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
Org. Lett. 10(17) , 3745-8, (2008)
The palladium-catalyzed cross-coupling reaction of triorganoindium reagents (R3In) with 5-bromo-2-chloropyrimidine proceeds chemoselectively, in good yields, to give 5-substituted-2-chloropyrimidines ...
Improved synthesis of 2,2'-bipyrimidine.J. Org. Chem. 67(18) , 6550-2, (2002)
A high-yield synthesis was developed for the preparation of 2,2'-bipyrimidine (1) using the Ullmann coupling of 2-iodopyrimidine. The new procedure was also used for the preparation of 4,4',6,6'-tetra...