D-Mannose

Names

[ Name ]:
D-Mannose

[Synonym ]:
D(+)-Maltose
alpha-D-mannose
(+)-Mannose
D-MAN
MFCD00064122
(2S,3S,4R,5R)-2,3,4,5,6-Pentahydroxyhexanal
Mannose
(2R,3R,4S,5S)-2,3,4,5,6-pentahydroxyhexanal
D-(+)-Mannose,D-Mannopyranose
CARUBINOSE
Mannose, D-
D-(+)-Mannose
aldehydo-D-mannose
L-(-)-Mannose
aldehydo-D-manno-hexose
D-mannose
D-MANOSE
D(+)-Mannose
MANNOSE,D-(+)
D-Mannopyranose
d-mannos
D-(+)-Maose
SEMINOSE
EINECS 222-392-4

Biological Activity

[Description]:

D-Mannose is a carbohydrate, which plays an important role in human metabolism, especially in the glycosylationof specific proteins.

[Related Catalog]:

Research Areas >> Others

Natural Products >> Saccharides and Glycosides

[Target]

Human Endogenous Metabolite

[References]

[1]. Genovese C, et al. Effects of a new combination of plant extracts plus d-mannose for the management of uncomplicated recurrent urinary tract infections. J Chemother. 2018 Apr;30(2):107-114.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
527.1±50.0 °C at 760 mmHg

[ Melting Point ]:
133-140ºC

[ Molecular Formula ]:
C₆H₁₂O₆

[ Molecular Weight ]:
180.156

[ Flash Point ]:
286.7±26.6 °C

[ Exact Mass ]:
180.063385

[ PSA ]:
118.22000

[ LogP ]:
-3.17

[ Vapour Pressure ]:
0.0±3.1 mmHg at 25°C

[ Index of Refraction ]:
1.573

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2940000000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2912491000

[ Summary ]:
2912491000. other aldehyde-alcohols. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

Articles

Rehmannia glutinosa (Gaertn.) DC. polysaccharide ameliorates hyperglycemia, hyperlipemia and vascular inflammation in streptozotocin-induced diabetic mice.

J. Ethnopharmacol. 164 , 229-38, (2015)

Rehmannia glutinosa (Gaertn.) DC. (RG) has been widely used as traditional Chinese herbal medicine for treatment of diabetes and its complications. The polysaccharide fraction of RG has been proposed ...

Preparation and structural characterization of poly-mannose synthesized by phosphoric acid catalyzation under microwave irradiation.

Carbohydr. Polym. 121 , 355-61, (2015)

Poly-mannose with molecular weight of 2.457 kDa was synthesized using d-mannose as substrate and phosphoric acid as catalyst under the condition of microwave irradiation for the first time. The optimu...

Type IV pilus glycosylation mediates resistance of Pseudomonas aeruginosa to opsonic activities of the pulmonary surfactant protein A.

Infect. Immun. 83(4) , 1339-46, (2015)

Pseudomonas aeruginosa is a major bacterial pathogen commonly associated with chronic lung infections in cystic fibrosis (CF). Previously, we have demonstrated that the type IV pilus (Tfp) of P. aerug...

Related Compounds

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