2-Propanone,1,1-dichloro-
Names
[ CAS No. ]:
513-88-2
[ Name ]:
2-Propanone,1,1-dichloro-
[Synonym ]:
unsym-dichloroacetone
1,1-DICHLORO-2-PROPANONE
1,1-DCA
1,1-Dichloropropanone
1,1-DICHLOROPROPANONE-2
dichloroacetone
1,1-dichloro-acetone
1,1-dichloromethyl methyl ketone
1,1-dichloro-2-propanon
EINECS 208-175-7
asym-Dichloroacetone
dichloropropanone
MFCD00009677
Chemical & Physical Properties
[ Density]:
1.327 g/mL at 25 °C(lit.)
[ Boiling Point ]:
117-118 °C(lit.)
[ Molecular Formula ]:
C3H4Cl2O
[ Molecular Weight ]:
126.96900
[ Flash Point ]:
99-100 °F
[ Exact Mass ]:
125.96400
[ PSA ]:
17.07000
[ LogP ]:
1.37910
[ Index of Refraction ]:
n20/D 1.446(lit.)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UC1428000
- CHEMICAL NAME :
- 2-Propanone, 1,1-dichloro-
- CAS REGISTRY NUMBER :
- 513-88-2
- BEILSTEIN REFERENCE NO. :
- 1740214
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C3-H4-Cl2-O
- MOLECULAR WEIGHT :
- 126.97
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3600 mg/kg/90D-I
- TOXIC EFFECTS :
- Liver - changes in liver weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases
MUTATION DATA
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TEST SYSTEM :
- Bacteria - Escherichia coli
- DOSE/DURATION :
- 30 mg/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 341,1,1994
Safety Information
[ Symbol ]:
GHS02, GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H226-H301
[ Precautionary Statements ]:
P301 + P310
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xn
[ Risk Phrases ]:
R10
[ Safety Phrases ]:
S16
[ RIDADR ]:
UN 1992 3/PG 3
[ WGK Germany ]:
3
[ RTECS ]:
UC1428000
[ Packaging Group ]:
III
[ Hazard Class ]:
3
[ HS Code ]:
2914700090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2914700090
[ Summary ]:
HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%
Articles
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Dermal contact with some organic disinfection by-products (DBPs) such as trihalomethanes in chlorinated drinking water has been established to be an important exposure route. We evaluated dermal absor...
Studies of the toxic interactions of disinfection by-products.Environ. Health Perspect. 69 , 203-7, (1986)
A large number and variety of compounds are formed in the process of chlorinating drinking water. The classes of compounds formed include trihalomethanes, haloacetic acids, haloacetonitriles, halophen...