Sclareol
Names
[ CAS No. ]:
515-03-7
[ Name ]:
Sclareol
[Synonym ]:
(1R,2R,4aS,8aS)-1-[(3R)-3-Hydroxy-3-methyl-4-penten-1-yl]-2,5,5,8a-tetramethyldecahydro-2-naphthalenol
(1R,2R,4aS,8aS)-1-[(3R)-3-Hydroxy-3-methylpent-4-en-1-yl]-2,5,5,8a-tetramethyldecahydronaphthalen-2-ol
SCLAREOL(RG)
EINECS 208-194-0
1-Naphthalenepropanol, α-ethenyldecahydro-2-hydroxy-α,2,5,5,8a-pentamethyl-, (αR,1R,2R,4aS,8aS)-
Labd-14-ene-8,13-diol, (13R)-
SCIADONIC ACID
(1R,2R,8aS)-Decahydro-1-(3-hydroxy-3-methyl-4-pentenyl)-2,5,5,8a-tetramethyl-2-naphthol
labd-14-ene-8,13(R)-diol
MFCD00869558
SCLAREOL,NATURAL
SCAREOL
Sclareol
(-)-sclareol
SCLAREOL(P)
(1R,2R,4aS,8aS)-1-[(3R)-3-Hydroxy-3-méthyl-4-pentèn-1-yl]-2,5,5,8a-tétraméthyldécahydro-2-naphtalénol
Biological Activity
[Description]:
[Related Catalog]:
[In Vitro]
[References]
Chemical & Physical Properties
[ Density]:
1.0±0.1 g/cm3
[ Boiling Point ]:
398.3±15.0 °C at 760 mmHg
[ Melting Point ]:
95-100 °C(lit.)
[ Molecular Formula ]:
C20H36O2
[ Molecular Weight ]:
308.499
[ Flash Point ]:
169.1±15.0 °C
[ Exact Mass ]:
308.271515
[ PSA ]:
40.46000
[ LogP ]:
5.54
[ Vapour Pressure ]:
0.0±2.1 mmHg at 25°C
[ Index of Refraction ]:
1.490
[ Storage condition ]:
2-8C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QK0301900
- CHEMICAL NAME :
- 1-Naphthalenepropanol, decahydro-alpha-ethenyl-2-hydroxy-alpha,2,5,5,8a-pent amethyl-, (1R-(1-alpha(R*),2-beta,4a-beta,8a-alpha))-
- CAS REGISTRY NUMBER :
- 515-03-7
- BEILSTEIN REFERENCE NO. :
- 2054148
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C20-H36-O2
- MOLECULAR WEIGHT :
- 308.56
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 30,115S,1992
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 30,115S,1992
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
2
[ RTECS ]:
QK0301900
[ HS Code ]:
2906199090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2906199090
[ Summary ]:
2906199090. cyclanic, cyclenic or cyclotherpenic alcohols. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%
Articles
J. Chromatogr. A. 1360 , 264-74, (2014)
Comprehensive two-dimensional gas chromatography (GC×GC) coupled with Mass Spectrometry (MS) is one of today's most powerful analytical platforms for detailed analysis of medium-to-high complexity sam...
Labdane diterpenoids from Salvia reuterana.Phytochemistry 108 , 264-9, (2014)
Three labdane diterpenoids, 14α-hydroxy-15-chlorosclareol (1), 14α-hydroxy-15-acetoxysclareol (2), and 6β-hydroxy-14α-epoxysclareol (3), together with the known diterpenoids sclareol (4), 6β-hydroxysc...
Isolation, chemical, and biotransformation routes of labdane-type diterpenes.Chem. Rev. 111(8) , 4418-52, (2011)