4-Methoxyphenylboronic acid
Names
[ CAS No. ]:
5720-07-0
[ Name ]:
4-Methoxyphenylboronic acid
[Synonym ]:
p-methoxy phenyl boronic acid
p-Anisylboronic acid
4-Boronoanisole
4-methoxy phenylboronic acid
MFCD00039139
p-Methoxyphenylboronic acid
para-methoxyphenylboronic acid
4-Methoxyphenylboronic acid
RARECHEM AH PB 0191
EINECS 216-845-5
(4-Methoxyphenyl)boronic acid
4-Anisylboronic acid
4-Methoxyphenylboron
4-Methoxybenzeneboronic acid
Boronic acid, B-(4-methoxyphenyl)-
p-Methoxybenzeneboronic acid
4-methoxyphenylboronicacid
Biological Activity
[Description]:
[Related Catalog]:
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
306.8±44.0 °C at 760 mmHg
[ Melting Point ]:
204-206 °C(lit.)
[ Molecular Formula ]:
C7H9BO3
[ Molecular Weight ]:
151.96
[ Flash Point ]:
139.3±28.4 °C
[ Exact Mass ]:
152.064468
[ PSA ]:
49.69000
[ LogP ]:
1.50
[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C
[ Index of Refraction ]:
1.524
[ Storage condition ]:
Refrigerator (+4°C)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CY8975000
- CHEMICAL NAME :
- Benzeneboronic acid, p-methoxy-
- CAS REGISTRY NUMBER :
- 5720-07-0
- BEILSTEIN REFERENCE NO. :
- 2936912
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C7-H9-B-O3
- MOLECULAR WEIGHT :
- 151.97
- WISWESSER LINE NOTATION :
- QBQR DO1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#00062
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36-S37/39
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
CY8975000
[ HS Code ]:
29310095
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2931900090
[ Summary ]:
2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%
Articles
Bioorg. Med. Chem. Lett. 19 , 2642-5, (2009)
Inhibition of the beta-carbonic anhydrases (CAs, EC 4.2.1.1) from the pathogenic fungi Cryptococcus neoformans (Can2) and Candida albicans (Nce103) with a series of aromatic, arylalkenyl- and arylalky...
Ruthenium(0)-catalyzed sp3 C-H bond arylation of benzylic amines using arylboronates.Org. Lett. 7th ed., 14 , 1930-1933, (2012)
A Ru-catalyzed direct arylation of benzylic sp(3) carbons of acyclic amines with arylboronates is reported. This highly regioselective and efficient transformation can be performed with various combin...
Tandem-type Pd(II)-catalyzed oxidative Heck reaction/intramolecular C-H amidation sequence: a novel route to 4-aryl-2-quinolinones.Chem. Commun. (Camb.) 36th ed., 48 , 4332-4334, (2012)
A novel catalytic method for synthesizing 4-aryl-2-quinolinones is reported. The process involves two mechanistically independent, sequential Pd(II)-catalyzed reactions--the oxidative Heck reaction an...