N-Hydroxysuccinimide
Names
[ CAS No. ]:
6066-82-6
[ Name ]:
N-Hydroxysuccinimide
[Synonym ]:
1-Hydroxy-2,5-pyrrolidinedione
N-hydroxy-succinimide
HOSu
N-Hydroxysuccinimide
2,5-Pyrrolidinedione, 1-hydroxy-
hydroxysuccinimide
succinimide, N-hydroxy-
N-hydroxyl succinimide
1-hydroxypyrrolidine-2,5-dione
1-Hydroxy-pyrrolidine-2,5-dione
Succinimide, N-hydroxy- (8CI)
MFCD00005516
EINECS 228-001-3
Chemical & Physical Properties
[ Density]:
1.6±0.1 g/cm3
[ Boiling Point ]:
262.4±23.0 °C at 760 mmHg
[ Melting Point ]:
95-98 °C(lit.)
[ Molecular Formula ]:
C4H5NO3
[ Molecular Weight ]:
115.087
[ Flash Point ]:
112.5±22.6 °C
[ Exact Mass ]:
115.026939
[ PSA ]:
57.61000
[ LogP ]:
-2.00
[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C
[ Index of Refraction ]:
1.600
[ Storage condition ]:
2-8°C
[ Stability ]:
Stable. Incompatible with strong oxidizing agents, acid chlorides, acid anhydrides, strong bases. Protect from moisture.
[ Water Solubility ]:
SOLUBLE
MSDS
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S22-S24/25-S26
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ HS Code ]:
2925190090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2925190090
[ Summary ]:
2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
Biomacromolecules 16(4) , 1382-9, (2015)
Natural biomolecules are often used to functionalize materials to achieve desired cell-material interactions. However, their applications can be limited owing to denaturation during the material funct...
DNase II-dependent DNA digestion is required for DNA sensing by TLR9.Nat. Commun. 6 , 5853, (2015)
DNase II digests DNA in endolysosomes. In the absence of DNase II, undigested DNA activates cytoplasmic DNA-sensing pathways. Little is known, however, about the role of DNase II in endolysosomal DNA ...
Anti-epidermal growth factor receptor conjugated mesoporous zinc oxide nanofibers for breast cancer diagnostics.Nanoscale 7(16) , 7234-45, (2015)
We report the fabrication of an efficient, label-free, selective and highly reproducible immunosensor with unprecedented sensitivity (femto-molar) to detect a breast cancer biomarker for early diagnos...