N-Hydroxysuccinimide
N-Hydroxysuccinimide structure
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Common Name | N-Hydroxysuccinimide | ||
|---|---|---|---|---|
| CAS Number | 6066-82-6 | Molecular Weight | 115.087 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 262.4±23.0 °C at 760 mmHg | |
| Molecular Formula | C4H5NO3 | Melting Point | 95-98 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 112.5±22.6 °C | |
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Aptamer-based polyvalent ligands for regulated cell attachment on the hydrogel surface.
Biomacromolecules 16(4) , 1382-9, (2015) Natural biomolecules are often used to functionalize materials to achieve desired cell-material interactions. However, their applications can be limited owing to denaturation during the material functionalization process. Therefore, efforts have been made to ... |
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DNase II-dependent DNA digestion is required for DNA sensing by TLR9.
Nat. Commun. 6 , 5853, (2015) DNase II digests DNA in endolysosomes. In the absence of DNase II, undigested DNA activates cytoplasmic DNA-sensing pathways. Little is known, however, about the role of DNase II in endolysosomal DNA sensing by TLR9. Here we show that DNase II is required for... |
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Anti-epidermal growth factor receptor conjugated mesoporous zinc oxide nanofibers for breast cancer diagnostics.
Nanoscale 7(16) , 7234-45, (2015) We report the fabrication of an efficient, label-free, selective and highly reproducible immunosensor with unprecedented sensitivity (femto-molar) to detect a breast cancer biomarker for early diagnostics. Mesoporous zinc oxide nanofibers (ZnOnFs) are synthes... |
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Oral delivery of probiotic expressing M cell homing peptide conjugated BmpB vaccine encapsulated into alginate/chitosan/alginate microcapsules.
Eur. J. Pharm. Biopharm. 88(3) , 768-77, (2014) Oral administration of live probiotics as antigen delivery vectors is a promising approach in vaccine development. However, the low survival of probiotics in the gastrointestinal tract limits this approach. Therefore, the aim of this study was the encapsulati... |
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Amelioration of radiation-induced oral cavity mucositis and distant bone marrow suppression in fanconi anemia Fancd2-/- (FVB/N) mice by intraoral GS-nitroxide JP4-039.
Radiat. Res. 182(1) , 35-49, (2014) The altered DNA damage response pathway in patients with Fanconi anemia (FA) may increase the toxicity of clinical radiotherapy. We quantitated oral cavity mucositis in irradiated Fanconi anemia Fancd2(-/-) mice, comparing this to Fancd2(+/-) and Fancd2(+/+) ... |
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Positive cooperativity between acceptor and donor sites of the peptidoglycan glycosyltransferase.
Biochem. Pharmacol. 93(2) , 141-50, (2015) The glycosyltransferases of family 51 (GT51) catalyze the polymerization of lipid II to form linear glycan chains, which, after cross linking by the transpeptidases, form the net-like peptidoglycan macromolecule. The essential function of the GT makes it an a... |
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Cardiolipin-incorporated liposomes with surface CRM197 for enhancing neuronal survival against neurotoxicity.
Int. J. Pharm. 473(1-2) , 334-44, (2014) CRM197-grafted liposomes containing cardiolipin (CL) (CRM197/CL-liposomes) were used to enhance the permeability of neuron growth factor (NGF) across the blood-brain barrier (BBB) for promoting the neuroprotective effect of NGF. CRM197/CL-liposoms were incuba... |
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Reduced filaggrin expression is accompanied by increased Staphylococcus aureus colonization of epidermal skin models.
Clin. Exp. Allergy 44(12) , 1515-24, (2014) Atopic dermatitis is an inflammatory skin disease that is characterized by a reduced skin barrier function, reduced filaggrin (FLG) expression as well as increased colonization by Staphylococcus aureus.This study focused on the possible involvement of FLG in ... |
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Development of antibodies for determination of alkylresorcinol metabolites in human urine and elucidation of ELISA cross-reactivity.
J. Immunol. Methods 413 , 12-24, (2014) Alkylresorcinols (ARs) are amphiphilic phenolic lipids and their two main metabolites, 3-(3,5-dihydroxyphenyl)-propanoic acid (DHPPA) and 3,5-dihydroxybenzoic acid (DHBA), can be used as biomarkers of whole grain wheat and rye intake. The aim of this study wa... |
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A two-enzyme immobilization approach using carbon nanotubes/silica as support.
Biotechnol. Prog. 31(1) , 42-7, (2015) Multiple enzyme mixtures are attractive for the production of many compounds at an industrial level. We report a practical and novel approach for coimmobilization of two enzymes. The system consists of a silica microsphere core coated with two layers of indiv... |