(R)-3-Hydroxybutanoic acid

Names

[ CAS No. ]:
625-72-9

[ Name ]:
(R)-3-Hydroxybutanoic acid

[Synonym ]:
(R)-3-HYDROXYBUTYRIC ACID
MFCD00066257
EINECS 210-909-6
D-3-Hydroxybutyric acid

Biological Activity

[Description]:

(R)-3-Hydroxybutanoic acid is a metabolite, and converted from acetoacetic acid catalyzed by 3-hydroxybutyrate dehydrogenase.

[Related Catalog]:

Research Areas >> Others

Natural Products >> Acids and Aldehydes

[Target]

Human Endogenous Metabolite

[In Vitro]

(R)-3-Hydroxybutanoic acid (D-3-Hydroxybutyric acid) is a metabolite, and converted from acetoacetic acid. Enhanced hepatic fatty acid oxidation results in the increased production of acetoacetic acid which is in turn converted to (R)-3-Hydroxybutanoic acid by a reaction catalyzed by 3-hydroxybutyrate dehydrogenase[1].

[References]

[1]. Ide T. Enzymatic-HPLC method to analyze D-3-hydroxybutyric acid in rat serum. Biosci Biotechnol Biochem. 2010;74(8):1578-82.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.195 g/cm3

[ Boiling Point ]:
269.2ºC at 760 mmHg

[ Melting Point ]:
49-50ºC(lit.)

[ Molecular Formula ]:
C₄H₈O₃

[ Molecular Weight ]:
104.10500

[ Flash Point ]:
112ºC

[ Exact Mass ]:
104.04700

[ PSA ]:
57.53000

[ Index of Refraction ]:
1.455

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2918199090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2918199090

[ Summary ]:
2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

Use of high-resolution proton nuclear magnetic resonance spectroscopy for rapid multi-component analysis of urine.

Clin. Chem. 30(3) , 426-32, (1984)

Numerous low-Mr metabolites--including creatinine, citrate, hippurate, glucose, ketone bodies, and various amino acids--have been identified in 400- and 500-MHz proton nuclear magnetic resonance (1H N...

1,5-anhydroglucitol and postprandial hyperglycemia as measured by continuous glucose monitoring system in moderately controlled patients with diabetes.

Diabetes Care 29(6) , 1214-9, (2006)

Postprandial hyperglycemia is often inadequately assessed in diabetes management. Serum 1,5-anhydroglucitol (1,5-AG) drops as serum glucose rises above the renal threshold for glucose and has been pro...

Can serum beta-hydroxybutyrate be used to diagnose diabetic ketoacidosis?

Diabetes Care 31(4) , 643-7, (2008)

Current criteria for the diagnosis of diabetic ketoacidosis (DKA) are limited by their nonspecificity (serum bicarbonate [HCO(3)] and pH) and qualitative nature (the presence of ketonemia/ketonuria). ...

Related Compounds

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