Xanthine oxidase

Names

[ Name ]:
Xanthine oxidase

[Synonym ]:
EINECS 232-657-6
MFCD00082145

Biological Activity

[Description]:

Xanthine oxidase is a xanthine oxidoreductase enzyme that generates reactive oxygen species (ROS), catalyzes the oxidation of hypoxanthine to xanthine, and further catalyzes the oxidation of xanthine to uric acid[1].

[Related Catalog]:

Research Areas >> Endocrinology

Research Areas >> Inflammation/Immunology

[In Vitro]

Xanthine oxidase rapidly and completely depletes hypoxanthine in human erythrocytes[2]. Xanthine oxidase (20 mU/mL, 72 h) inhibits growth of Plasmodium falciparum in human erythrocytes[2]. Xanthine oxidase (0.02 U/mL, 6 h) reduces the viability of postnatal cerebellar granule neurons obtained from 8-day old Sprague-Dawley rat pups[3].

Chemical & Physical Properties

[ Appearance of Characters ]:
powder | brown

[ Storage condition ]:
2-8°C

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
RQ8455000

[ HS Code ]:
35079090

Articles

Changes in mitochondrial membrane composition and oxidative status during rapid growth, maturation and aging in zebrafish, Danio rerio.

Biochim. Biophys. Acta 1841(7) , 1003-11, (2014)

Considering membranes and membrane components as possible pacemakers of the main processes taking place inside mitochondria, changes in phospholipids or fatty acids could play a central role linking d...

Study of anti-inflammatory activities of α-D-glucosylated eugenol.

Arch. Pharm. Res. 36(1) , 109-15, (2013)

Inflammation is an immune response against a variety of noxious stimuli, such as infection, chemicals, and physical injury. Eugenol, a natural phenolic extract, has drawn much attention for its variou...

[Influence of oxidative stress on the level of genes expression Tgfb1 and Hgf in rat liver upon long-term gastric hypochlorhydria and administration of multiprobiotic Symbiter].

Ukr. Biokhim. Zh. 85(5) , 114-23, (2013)

Free-radical processes upon long-term omeprazole-induced gastric hypochlorhydria in the rat liver were researched. Intensification of oxidative processes in the liver tissue upon gastric hypoacid stat...

Related Compounds

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