947-92-2

947-92-2 structure

Name: Cyclohexanamine,N-cyclohexyl-N-nitroso-
Chemical Name: N,N-dicyclohexylnitrous amide
CAS Number: 947-92-2
Molecular Formula: C₁₂H₂₂N₂O
Molecular Weight: 210.31600
Catalog: Research Areas Endocrinology
Create Date: 2016-05-07 01:40:09
Modify Date: 2024-01-14 17:55:27
N-Nitrosodicyclohexylamine (NDCHA) is a N-nitrosocompound with anti-androgenic activities. N-Nitrosodicyclohexylamine shows the competitive binding to androgen receptor (AR) against 5α-dihydrotestosterone and decreased the level of AR protein[1].

Name	N,N-dicyclohexylnitrous amide
Synonyms	N-dicyclohexylnitrosamine N-cyclohexyl-N-nitrosocyclohexanamine DICYCLOHEXYLAMINE,N-NITROSO N-Nitrosodicyclohexylamin Dicyclohexylnitrosamine Dicyclohexyl-nitroso-amin dicyclohexyl-nitroso-amine Cyclohexanamine,N-cyclohexyl-N-nitroso Dicyclohexylnitrosamin N-Nitrosodicyclohexylamine

Description	N-Nitrosodicyclohexylamine (NDCHA) is a N-nitrosocompound with anti-androgenic activities. N-Nitrosodicyclohexylamine shows the competitive binding to androgen receptor (AR) against 5α-dihydrotestosterone and decreased the level of AR protein[1].
Related Catalog	Research Areas >> Endocrinology Signaling Pathways >> Others >> Androgen Receptor
References	[1]. Hari, Sayaka, et al. (2006). Anti-Androgenic Activity of N-Nitrosodibenzylamine, N-Nitrosodiphenylamine and N-Nitrosodicyclohexylamine. JOURNAL OF HEALTH SCIENCE, 52(5), 522-531.

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ZEKBAI Zeitschrift fuer Krebsforschung. (Berlin, Fed. Rep. Ger.) V.1-75, 1903-71. For publisher information, see JCROD7. Volume(issue)/page/year: 69,103,1967