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62625-28-9

62625-28-9 structure
62625-28-9 structure
  • Name: Bromophenol blue sodium
  • Chemical Name: Bromophenol Blue sodium salt
  • CAS Number: 62625-28-9
  • Molecular Formula: C19H9Br4NaO5S
  • Molecular Weight: 691.94300
  • Catalog: Biochemical Biochemical reagent Biological dye
  • Create Date: 2018-07-26 10:50:36
  • Modify Date: 2024-01-13 13:23:30
  • Bromophenol blue sodium is a pH indicator. It changes from yellow at pH 3.0 to blue at pH 4.6. Bromophenol blue sodium is also used as a tracking dye to monitor the process of agarose gel electrophoresis and polyacrylamide gel electrophoresis[1][2].

Name Bromophenol Blue sodium salt
Synonyms sodium,2-[(3,5-dibromo-4-hydroxyphenyl)-(3,5-dibromo-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]benzenesulfonate
EINECS 204-086-2
MFCD00013793
Description Bromophenol blue sodium is a pH indicator. It changes from yellow at pH 3.0 to blue at pH 4.6. Bromophenol blue sodium is also used as a tracking dye to monitor the process of agarose gel electrophoresis and polyacrylamide gel electrophoresis[1][2].
Related Catalog
References

[1]. Shokrollahi A, Zare E. Determination of acidity constants of bromophenol blue and phenol red indicators by solution scanometric method and comparison with spectrophotometric results. Journal of Molecular Liquids, 2016, 219: 1165-1171.

[2]. Gish G, Eckstein F. DNA and RNA sequence determination based on phosphorothioate chemistry. Science. 1988 Jun 10;240(4858):1520-2.  

Density 0.954 g/mL at 20ºC
Melting Point >300ºC
Molecular Formula C19H9Br4NaO5S
Molecular Weight 691.94300
Exact Mass 687.68000
PSA 102.88000
LogP 7.62510
Storage condition Store at RT.
Stability Stable. Incompatible with strong oxidizing agents.
Water Solubility soluble
Name: Bromophenol Blue Sodium Salt Reagent ACS Material Safety Data Sheet
Synonym: 4,4'-(3h-1,2 benzoxathiol-3-ylidene)bis(2,6-dibromophenol s,s-dioxide monosodium sal
CAS: 62625-28-9
Section 1 - Chemical Product MSDS Name:Bromophenol Blue Sodium Salt Reagent ACS Material Safety Data Sheet
Synonym:4,4'-(3h-1,2 benzoxathiol-3-ylidene)bis(2,6-dibromophenol s,s-dioxide monosodium sal

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
62625-28-9 Bromophenol blue, sodium salt 100 263-653-2
Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
May cause eye irritation. This product contains an anionic dye.
Similar dyes have not caused injury to the cornea or conjunctiva in documented exposure cases with human or rabbit eyes.
Skin:
May cause skin irritation.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic:
No information found.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use agent most appropriate to extinguish fire. Use water spray, dry chemical, carbon dioxide, or appropriate foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.

Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Use with adequate ventilation.
Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 62625-28-9: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: Not available.
Odor: none reported
pH: Not available.
Vapor Pressure: Not applicable.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C19H9Br4NaO5S
Molecular Weight: 691.95

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, dust generation, excess heat.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, oxides of sulfur, irritating and toxic fumes and gases, carbon dioxide, hydrogen bromide.
Hazardous Polymerization: Has not been reported.

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 62625-28-9 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
Bromophenol blue, sodium salt - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
WGK (Water Danger/Protection)
CAS# 62625-28-9: No information available.
Canada
CAS# 62625-28-9 is listed on Canada's DSL List.
CAS# 62625-28-9 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 62625-28-9 is listed on the TSCA inventory.


SECTION 16 - ADDITIONAL INFORMATION
N/A
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S37/39
RIDADR UN 2265 3
WGK Germany 3
RTECS SJ7453000

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62625-28-9 structure

62625-28-9

Literature: Angewandte Chemie - International Edition, , vol. 52, # 35 p. 9238 - 9241 Angew. Chem., , vol. 125, # 35 p. 49408 - 49411
Precursor  1

DownStream  0