22172-15-2
22172-15-2 structure
- Name: Norswertianin
- Chemical Name: norswertianin
- CAS Number: 22172-15-2
- Molecular Formula: C13H8O6
- Molecular Weight: 260.19900
- Catalog: Signaling Pathways Autophagy Autophagy
- Create Date: 2016-07-24 02:13:09
- Modify Date: 2024-01-11 10:24:42
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Norswertianin, a xanthone compound, serves as a powerful anti-glioma compound. Norswertianin induces GBM cells differentiation through oxidative stress and Akt/mTOR dependent autophagy[1].
| Name | norswertianin |
|---|---|
| Synonyms |
1,2,6,8-tetrahydroxyxanthen-9-one
1,3,7,8-Tetrahydroxyxanthone 1,2,6,8-tetrahydroxy-xanthen-9-one 1,2,6,8-Tetrahydroxyxanthone Norswertianin Xanthen-9-one,1,2,6,8-tetrahydroxy 1,2,6,8-Tetrahydroxy-9H-xanthen-9-one 1,2,6,8-Tetrahydroxy-xanthen-9-on 1,3,7,8-Tetrahydroxyxanthon norswetianin |
| Description | Norswertianin, a xanthone compound, serves as a powerful anti-glioma compound. Norswertianin induces GBM cells differentiation through oxidative stress and Akt/mTOR dependent autophagy[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Norswertianin (12.5-50 µM; 48 hours) stimulats expression of GFAP and β-tubulin in U251 cells[1]. Norswertianin (40 µM; 48 hours) causes the appearance of elongated processes in U251 cells, associated with G2/M cell cycle arrest[1]. Norswertianin (40 µM; 48 hours) exhibits an increase in intracellular acidification and LC3 conversion[1]. |
| References |
| Density | 1.766g/cm3 |
|---|---|
| Boiling Point | 601.7ºC at 760mmHg |
| Molecular Formula | C13H8O6 |
| Molecular Weight | 260.19900 |
| Flash Point | 240.4ºC |
| Exact Mass | 260.03200 |
| PSA | 111.13000 |
| LogP | 1.76860 |
| Vapour Pressure | 4.49E-15mmHg at 25°C |
| Index of Refraction | 1.801 |
| HS Code | 2932999099 |
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22172-15-2 |
| Literature: Dalal et al. Journal of the Indian Chemical Society, 1953 , vol. 30, p. 457,459, 461 |
| Precursor 1 | |
|---|---|
| DownStream 0 | |
| HS Code | 2932999099 |
|---|---|
| Summary | 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |