DC Chemicals Limited
China
Product Name: Norswertianin
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: NORSWERTIANIN
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

22172-15-2

22172-15-2 structure

22172-15-2 structure

Name: Norswertianin
Chemical Name: norswertianin
CAS Number: 22172-15-2
Molecular Formula: C₁₃H₈O₆
Molecular Weight: 260.19900
Catalog: Signaling Pathways Autophagy Autophagy
Create Date: 2016-07-24 02:13:09
Modify Date: 2024-01-11 10:24:42
Norswertianin, a xanthone compound, serves as a powerful anti-glioma compound. Norswertianin induces GBM cells differentiation through oxidative stress and Akt/mTOR dependent autophagy[1].

Name	norswertianin
Synonyms	1,2,6,8-tetrahydroxyxanthen-9-one 1,3,7,8-Tetrahydroxyxanthone 1,2,6,8-tetrahydroxy-xanthen-9-one 1,2,6,8-Tetrahydroxyxanthone Norswertianin Xanthen-9-one,1,2,6,8-tetrahydroxy 1,2,6,8-Tetrahydroxy-9H-xanthen-9-one 1,2,6,8-Tetrahydroxy-xanthen-9-on 1,3,7,8-Tetrahydroxyxanthon norswetianin

Description	Norswertianin, a xanthone compound, serves as a powerful anti-glioma compound. Norswertianin induces GBM cells differentiation through oxidative stress and Akt/mTOR dependent autophagy[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Autophagy >> Autophagy
In Vitro	Norswertianin (12.5-50 µM; 48 hours) stimulats expression of GFAP and β-tubulin in U251 cells[1]. Norswertianin (40 µM; 48 hours) causes the appearance of elongated processes in U251 cells, associated with G2/M cell cycle arrest[1]. Norswertianin (40 µM; 48 hours) exhibits an increase in intracellular acidification and LC3 conversion[1].
References	[1]. Gordana Tovilovic-Kovacevic, et al. Xanthone-rich extract from Gentiana dinarica transformed roots and its active component norswertianin induce autophagy and ROS-dependent differentiation of human glioblastoma cell line. Phytomedicine

Density	1.766g/cm3
Boiling Point	601.7ºC at 760mmHg
Molecular Formula	C₁₃H₈O₆
Molecular Weight	260.19900
Flash Point	240.4ºC
Exact Mass	260.03200
PSA	111.13000
LogP	1.76860
Vapour Pressure	4.49E-15mmHg at 25°C
Index of Refraction	1.801

HS Code	2932999099

25991-81-5 structure

25991-81-5

~%

22172-15-2 structure

22172-15-2

Literature: Dalal et al. Journal of the Indian Chemical Society, 1953 , vol. 30, p. 457,459, 461

Precursor 1
25991-81-5
DownStream 0

HS Code	2932999099
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%