851956-02-0

851956-02-0 structure

Name: RuBi-4AP
Chemical Name: L-Tryptophan
CAS Number: 851956-02-0
Molecular Formula: C₃₀H₂₈Cl₂N₈Ru
Molecular Weight: 672.57
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Potassium Channel
Create Date: 2018-07-15 12:45:57
Modify Date: 2024-01-06 07:50:09
RuBi-4AP, a derivative of 4-aminopyridine (4AP; HY-B0604), is a caged Kv channel blocker. RuBi-4AP contains a photolabile protecting group, allowing its effect to be controlled precisely in both space and time with light. RuBi-4AP can be used for the research of neuronal excitability, synaptic transmission, and signal propagation[1][2].

Name	L-Tryptophan
Synonyms	(S)-(-)-2-Amino-3-(3-indolyl)propionic Acid

Description	RuBi-4AP, a derivative of 4-aminopyridine (4AP; HY-B0604), is a caged Kv channel blocker. RuBi-4AP contains a photolabile protecting group, allowing its effect to be controlled precisely in both space and time with light. RuBi-4AP can be used for the research of neuronal excitability, synaptic transmission, and signal propagation[1][2].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel
References	[1]. Zayat L, et al. A new strategy for neurochemical photodelivery: metal-ligand heterolytic cleavage. J Am Chem Soc. 2003 Jan 29;125(4):882-3. [2]. Rowan MJ, et al. Distinct Kv channel subtypes contribute to differences in spike signaling properties in the axon initial segment and presynaptic boutons of cerebellar interneurons. J Neurosci. 2014 May 7;34(19):6611-23.