21618-67-7

21618-67-7 structure
21618-67-7 structure
  • Name: 5-(Trifluoromethyl)uridine
  • Chemical Name: 5-(trifluoromethyl)-uridine
  • CAS Number: 21618-67-7
  • Molecular Formula: C10H11F3N2O6
  • Molecular Weight: 312.20
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
  • Create Date: 2018-08-06 12:48:23
  • Modify Date: 2024-01-02 12:02:53
  • 5-(Trifluoromethyl)uridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name 5-(trifluoromethyl)-uridine
Synonyms 5-trifluorouridine
500Mg,1g
5-trifluorothymidine
5-(trifluoromethyl)uridine
Description 5-(Trifluoromethyl)uridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Density 1.765g/cm3
Molecular Formula C10H11F3N2O6
Molecular Weight 312.20
Exact Mass 312.05700
PSA 124.78000
Index of Refraction 1.563

~23%

21618-67-7 structure

21618-67-7

Literature: Tosoh Corporation; Tosoh F- Tech Inc.; SAGAMI CHEMICAL RESEARCH CENTER Patent: EP1947092 A1, 2008 ; Location in patent: Page/Page column 42 ;

~70%

21618-67-7 structure

21618-67-7

Literature: Kobayashi, Yoshiro; Yamamoto, Kenjiro; Asai, Toyohira; Nakano, Masanori; Kumadaki, Itsumaro Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 2755 - 2761

~%

21618-67-7 structure

21618-67-7

Literature: Kobayashi, Yoshiro; Yamamoto, Kenjiro; Asai, Toyohira; Nakano, Masanori; Kumadaki, Itsumaro Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 2755 - 2761