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1393-48-2

1393-48-2 structure
1393-48-2 structure
  • Name: Thiostrepton
  • Chemical Name: thiostrepton
  • CAS Number: 1393-48-2
  • Molecular Formula: C72H85N19O18S5
  • Molecular Weight: 1664.89000
  • Catalog: API Antibiotics Other antibiotics
  • Create Date: 2018-03-26 08:00:00
  • Modify Date: 2024-01-02 17:17:48
  • Thiostrepton is a natural cyclic oligopeptide antibiotic, is a natural product of the ribosomally synthesized and post-translationally modified peptide (RiPP) class.

Name thiostrepton
Synonyms MFCD00135828
Thiostrepton
EINECS 215-734-9
Description Thiostrepton is a natural cyclic oligopeptide antibiotic, is a natural product of the ribosomally synthesized and post-translationally modified peptide (RiPP) class.
Related Catalog
Density 1.64 g/cm3
Melting Point 248-257°C (dec.)
Molecular Formula C72H85N19O18S5
Molecular Weight 1664.89000
Exact Mass 1663.49000
PSA 701.00000
LogP 4.08640
Index of Refraction 1.768
Storage condition -20°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XN6300100
CHEMICAL NAME :
Thiostrepton
CAS REGISTRY NUMBER :
1393-48-2
LAST UPDATED :
199506
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C72-H85-N19-O18-S5
MOLECULAR WEIGHT :
1665.06

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ANTCAO Antibiotics and Chemotherapy (Washington, DC). (Washington, DC) V.1-12, 1951-62. For publisher information, see CLMEA3. Volume(issue)/page/year: 6,63,1956
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 4(1),396,1980
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
41 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 4(1),396,1980
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intramuscular
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 4(1),397,1980
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xn
Risk Phrases 22
Safety Phrases 22-24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS XN6300100