161973-10-0
161973-10-0 structure
- Name: Esomeprazole
- Chemical Name: esomeprazole magnesium
- CAS Number: 161973-10-0
- Molecular Formula: C34H36MgN6O6S2
- Molecular Weight: 713.121
- Catalog: API Digestive system medication Acid and gastric mucosal protective drugs
- Create Date: 2018-06-13 11:29:15
- Modify Date: 2026-07-02 11:22:28
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Esomeprazole magnesium is an inhibitor of H+, K+-ATPase, effectively used in the research of upper intestinal disorder.
| Name | esomeprazole magnesium |
|---|---|
| Synonyms |
Magnesium 5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]benzimidazol-1-ide
Nexium (S)-5-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole, magnesium salt (2:1) NEXIUM(esomrazolemagnesium) EsMeprazole Magne-siuM Trihydrate sulfonium, hydroxy(6-methoxy-1H-benzimidazol-2-yl)[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]-, inner salt, magnesium salt (2:1) (-)-Omrazole Magnesium H 199/18 Esomrazole magnesium Esomrazole magnesium(API) Esomrazole Magnesium, 10 mM in DMSO Magnesium bis(5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl}benzimidazol-1-ide) Esomeprazole magnesium Esomrazole magnesium API ESOMRAZOLE MAGNESIUM/SODIUM Magnesium Bis[6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]benzimidazol-1-ide] Magnesium bis(5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}benzimidazol-1-ide) Bis(5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}benzimidazol-1-ide) magnesium Esomrazole Magnesium(Random Configuration) (-)-Omeprazole magnesium H-199/18 omeprazole magnesium Esomrazole magnesium Esomrazole magnesium (S-Omrazole magnesium) magnesium 5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methanesulfinyl]-1H-1,3-benzodiazol-1-ide 6-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methanesulfinyl]-1H-1,3-benzodiazol-1-ide Esomrazole magnesium //BP EsoMrazole MagnesiuM(NexiuM) Solvate of potassium 5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}benzimidazol-1-ide with ethanol(1:2) Esomrazole magneslum S-Form magnesium salt Chebi 5-Methoxy-2-((S)-((4-Methoxy-3,5-diMethyl-2-pyridyl)Methyl)sulfinyl-1H-benziMidazole MagnesiuM salt (T-4-(S),(S))-Bis(5-methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)sulfinyl)-1H-benzimidazolato)magnesium ESOMRAZOLE MAGNESIUM , NON-STERILE, BULK DRUG SUBSTANCE Esomrazole magnesium 5-Methoxy-2-[(S)-(4-methoxy-3,5-dimethyl-2-pyridinylmethyl)sulfinyl]-1H-benzimidazole magnesium salt (S)-Omeprazole magnesium Esomrazole magnesiumQ: What is Esomrazole magnesium Q: What is the CAS Number of Esomrazole magnesium Q: What is the storage condition of Esomrazole magnesium Q: What e the applications of Esomrazole magnesium MagnesiuM,bis[6-Methoxy-2-[(S)-[(4-Methoxy-3,5-diMethyl-2-pyridinyl)Methyl]sulfinyl-kO]-1H-benziMidazolato-kN3]-, (T-4) (T-4)-Bis(5-methoxy-2-((S)-((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)sulfinyl-kO)-1H-benzimidazolato-kN1)magnesium EsMrazole Magne-siuM Trihydrate 1H-Benzimidazole, 5-methoxy-2-[(S)-[(1S)-(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, magnesium salt (2:1) Magnesium bis{(6-methoxybenzimidazol-1-id-2-yl)[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfoniumolate} ESOMRAZOLE MAGNESIUM SAMPLE (T-4)-bis[6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl-κO]-1H-benzimidazolato-κN3]-magnesium |
| Description | Esomeprazole magnesium is an inhibitor of H+, K+-ATPase, effectively used in the research of upper intestinal disorder. |
|---|---|
| Related Catalog | |
| Target |
H+, K+-ATPase[1] |
| In Vitro | Esomeprazole magnesium is an inhibitor of H+, K+-ATPase[1]. |
| In Vivo | Esomeprazole magnesium (0.5, 5, 50 mg/kg/day, p.o.) produces increased gastric total antioxidant capacity, decreases gastric lipid peroxide levels, significantly increases superoxide dismutase levels, but shows no obvious effect on colonic lipid peroxide levels in mice[1]. |
| Animal Admin | Mice[1] In this 10-day supplementation experiment, mice (n = 10/group) receive the following: 1) as a control group, only the vehicle for dissolution of Esomeprazole (PEG-400) given orally once daily by gastric gavage; 2) Esomeprazole 0.5 mg/kg in an equivalent volume of PEG-400 given orally once daily by gastric lavage; 3) Esomeprazole 5 mg/kg in an equivalent volume of PEG-400 given orally once daily by gastric lavage; and 4) Esomeprazole 50 mg/kg in an equivalent volume of PEG-400 given orally once daily by gastric lavage[1]. |
| References |
| Boiling Point | 600ºC at 760 mmHg |
|---|---|
| Molecular Formula | C34H36MgN6O6S2 |
| Molecular Weight | 713.121 |
| Flash Point | 316.7ºC |
| Exact Mass | 712.198792 |
| PSA | 186.82000 |
| LogP | 6.78900 |
| Vapour Pressure | 2.35E-14mmHg at 25°C |
| Storage condition | -20℃ |