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Dayang Chem (Hangzhou) Co., Ltd.
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Henan Tianfu Chemical Co., Ltd.
China
Product Name: 4-Hydroxydiphenylamine
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122-37-2

122-37-2 structure

122-37-2 structure

Name: 4-Hydroxydiphenylamine
Chemical Name: 4-Hydroxydiphenylamine
CAS Number: 122-37-2
Molecular Formula: C₁₂H₁₁NO
Molecular Weight: 185.22200
Catalog: Pharmaceutical intermediate Diphenylamine intermediate
Create Date: 2018-07-26 11:39:34
Modify Date: 2026-07-01 18:44:07

Name	4-Hydroxydiphenylamine
Synonyms	4-Hydroxydiphenylamine ISO 9001：2015 REACH 4-anilinophenol 4-(phenylamino)-phenol 4-Oxydiphenylamine 4-(N-PHENYLAMINO)PHENOL P-ANILINOPHENOL 4-(phenylamino)-pheno p-(Phenylamino)phenol Phenol, p-anilino vti1 4-HYDROXYDIPHENYLAMINE p-anilino-pheno p-Anilinophenol 4-HYDROXY DIPHENYLAMINE (PEDIA) Diphenylamine, 4-hydroxy N-Phenyl-p-aminophenol Phenyl-p-aminophenol 4-Hydroxydiphenylamine > P-HYDROXYDIPHENYLAMINE vti1-rp1 4-ANILINOPHENOL VTI1L EINECS 204-538-9 4-ANILINO-1-HYDROXYBENZENE v-SNE VTI1L1 Phenol,4-(phenylamino) PA-ANILINOPHENOL 4-Hydroxyphenylphenylamine pa-Hydroxydifenylamin VTI2 p-Oxydiphenylamine 4-HydroxydiphenylaMine 4-Hydroxy-1,1'-diphenylamine 4-hydroxy-diphenylamin Pa-hydroxydiphenylamine MFCD00020142 p-Hydroxydifenylamin VTI1-LIKE VTI 1

Density	1.203 g/cm3
Boiling Point	190°C
Melting Point	67-73°C
Molecular Formula	C₁₂H₁₁NO
Molecular Weight	185.22200
Flash Point	209°C
Exact Mass	185.08400
PSA	32.26000
LogP	3.20880
Vapour Pressure	8.52E-05mmHg at 25°C
Index of Refraction	1.67

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SJ6950000

CHEMICAL NAME :: Phenol, p-anilino-

CAS REGISTRY NUMBER :: 122-37-2

BEILSTEIN REFERENCE NO. :: 0511942

LAST UPDATED :: 199710

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C12-H11-N-O

MOLECULAR WEIGHT :: 185.24

WISWESSER LINE NOTATION :: QR DMR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,698,1986 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3300 mg/kg

TOXIC EFFECTS :: Autonomic Nervous System - other (direct) parasympathomimetic Behavioral - general anesthetic Blood - methemoglobinemia-carboxyhemoglobin

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 27(3),52,1983

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2120 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 12,1123,1962

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 60 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 12,1123,1962

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 3300 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - cyanosis

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 40(10),114,1975 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 0.5 mg/m3 JAN 1993

Hazard Codes	Xn
Risk Phrases	R37/38;R41
Safety Phrases	S26-S36/37/39-S36/39
RIDADR	UN2811
RTECS	SJ6950000
Packaging Group	III
Hazard Class	6.1
HS Code	2922299090

Precursor 9
108-86-1 123-30-8 101-02-0 637-88-7
591-50-4 13515-47-4 100-58-3 830-03-5
13871-68-6
DownStream 10
19099-70-8 1927-44-2 29653-73-4 29653-77-8
25069-86-7 824-69-1 2406-04-4 34865-89-9
101-73-5 1020-54-8

HS Code	2922299090
Summary	2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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