521-48-2

521-48-2 structure
521-48-2 structure
  • Name: Isoxanthohumol
  • Chemical Name: isoxanthohumol
  • CAS Number: 521-48-2
  • Molecular Formula: C21H22O5
  • Molecular Weight: 354.39600
  • Catalog: Signaling Pathways Anti-infection HSV
  • Create Date: 2016-08-15 03:45:20
  • Modify Date: 2024-01-09 20:36:44
  • Isoxanthohumol is a prenylflavonoid from hops and beer. Isoxanthohumol exhibits an antiproliferative activity against several human cancer cell lines. Isoxanthohumol inhibits the development of lung metastatic foci in tumor-challenged animals. Isoxanthohumol shows an antiviral activity towards herpes viruses (HSV1 and HSV2) and bovine viral diarrhea virus (BVDV)[1][2].

Name isoxanthohumol
Synonyms 4',7-DIHYDROXY-5-METHOXY-8-PRENYLFLAVANONE
Isoxanthohumol
Description Isoxanthohumol is a prenylflavonoid from hops and beer. Isoxanthohumol exhibits an antiproliferative activity against several human cancer cell lines. Isoxanthohumol inhibits the development of lung metastatic foci in tumor-challenged animals. Isoxanthohumol shows an antiviral activity towards herpes viruses (HSV1 and HSV2) and bovine viral diarrhea virus (BVDV)[1][2].
Related Catalog
Target

HSV-1

HSV-2

References

[1]. Żołnierczyk AK, et al. Isoxanthohumol--Biologically active hop flavonoid. Fitoterapia. 2015 Jun;103:71-82.

[2]. Krajnović T, et al. The hop-derived prenylflavonoid isoxanthohumol inhibits the formation of lung metastasis in B16-F10 murine melanoma model. Food Chem Toxicol. 2019 Jul;129:257-268.

Molecular Formula C21H22O5
Molecular Weight 354.39600
Exact Mass 354.14700
PSA 75.99000
LogP 4.32160
RIDADR NONH for all modes of transport
HS Code 2932999099

~85%

521-48-2 structure

521-48-2

Literature: Aniol, Miroslaw; Szymanska, Katarzyna; Zolnierczyk, Anna Tetrahedron, 2008 , vol. 64, # 40 p. 9544 - 9547

~%

521-48-2 structure

521-48-2

Detail
Literature: Biodynamics Patent: EP1543834 A1, 2005 ; Location in patent: Page/Page column 7; 8 ;
HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%