Isoxanthohumol

Modify Date: 2024-01-09 20:36:44

Isoxanthohumol structure	Common Name	Isoxanthohumol
	CAS Number	521-48-2	Molecular Weight	354.39600
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₂₂O₅	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	N/A

Use of Isoxanthohumol

Isoxanthohumol is a prenylflavonoid from hops and beer. Isoxanthohumol exhibits an antiproliferative activity against several human cancer cell lines. Isoxanthohumol inhibits the development of lung metastatic foci in tumor-challenged animals. Isoxanthohumol shows an antiviral activity towards herpes viruses (HSV1 and HSV2) and bovine viral diarrhea virus (BVDV)[1][2].

Name	isoxanthohumol
Synonym	More Synonyms

Description	Isoxanthohumol is a prenylflavonoid from hops and beer. Isoxanthohumol exhibits an antiproliferative activity against several human cancer cell lines. Isoxanthohumol inhibits the development of lung metastatic foci in tumor-challenged animals. Isoxanthohumol shows an antiviral activity towards herpes viruses (HSV1 and HSV2) and bovine viral diarrhea virus (BVDV)[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Anti-infection >> HSV Research Areas >> Infection
Target	HSV-1 HSV-2
References	[1]. Żołnierczyk AK, et al. Isoxanthohumol--Biologically active hop flavonoid. Fitoterapia. 2015 Jun;103:71-82. [2]. Krajnović T, et al. The hop-derived prenylflavonoid isoxanthohumol inhibits the formation of lung metastasis in B16-F10 murine melanoma model. Food Chem Toxicol. 2019 Jul;129:257-268.

Molecular Formula	C₂₁H₂₂O₅
Molecular Weight	354.39600
Exact Mass	354.14700
PSA	75.99000
LogP	4.32160

Isoxanthohumol MSDS(Chinese)

RIDADR	NONH for all modes of transport
HS Code	2932999099

Xanthohumol

CAS#:569-83-5

~85%

Isoxanthohumol

CAS#:521-48-2

Literature: Aniol, Miroslaw; Szymanska, Katarzyna; Zolnierczyk, Anna Tetrahedron, 2008 , vol. 64, # 40 p. 9544 - 9547

Xanthohumol

CAS#:569-83-5

Desmethylxanthohumol

CAS#:115063-39-3

rac 8-Prenylnar...

CAS#:68682-02-0

Isoxanthohumol

CAS#:521-48-2

Detail

Literature: Biodynamics Patent: EP1543834 A1, 2005 ; Location in patent: Page/Page column 7; 8 ;

Precursor 2
CAS#:569-83-5 Xanthohumol CAS#:115063-39-3 Desmethylxanthohumol
DownStream 2
CAS#:569-83-5 Xanthohumol CAS#:68682-02-0 rac 8-Prenylnar...

HS Code	2932999099
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

A comprehensive characterisation of beer polyphenols by high resolution mass spectrometry (LC-ESI-LTQ-Orbitrap-MS).

Food Chem. 169 , 336-43, (2014)

Beer is the second most consumed alcoholic beverage in Europe and shown by the European Prospective Investigation into Cancer and Nutrition cohort study to be the main food contributor to hydroxybenzo...

4',7-DIHYDROXY-5-METHOXY-8-PRENYLFLAVANONE

Isoxanthohumol